{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T10:48:01Z","timestamp":1791110881559,"version":"4.1.0"},"reference-count":13,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2015,7,14]],"date-time":"2015-07-14T00:00:00Z","timestamp":1436832000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2016,11]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Peritoneal carcinomatosis (PC<\/jats:styled-content>) results from the secondary spread of many intraabdominal tumour types, such as colorectal malignancy (colorectal cancer, CRC<\/jats:styled-content>), disseminated peritoneal adenomucinosis (DPAM<\/jats:styled-content>), appendiceal cancer, ovarian carcinoma, sarcoma or from the occurrence of primary peritoneal disease such as peritoneal mesothelioma. The combination of cytoreductive surgery (CRS<\/jats:styled-content>) and hyperthermic intraperitoneal chemotherapy (HIPEC<\/jats:styled-content>) has seen improvements in survival in selected cases of these cancers.<\/jats:p><\/jats:sec>Methods<\/jats:title>Between 1996 and 2014, a prospective database of 675 patients was created for the peritonectomy unit at our hospital. In total, 827 peritonectomy procedures (including redo CRS<\/jats:styled-content>) were performed for the major subgroups of PC<\/jats:styled-content>: DPAM<\/jats:styled-content> 220; appendiceal cancer (peritoneal mucinous adenocarcinoma (PMCA<\/jats:styled-content>)) 191; CRC<\/jats:styled-content> 234; diffuse malignant peritoneal mesothelioma (DMPM<\/jats:styled-content>) 73 and others 109. There were 152 redo\u2010peritonectomy procedures within the total mentioned earlier (CRC<\/jats:styled-content> 26; DPAM<\/jats:styled-content> 58; DMPM<\/jats:styled-content> 18; appendix 40; other 10).<\/jats:p><\/jats:sec>Results<\/jats:title>The 5\u2010year survivals for DPAM<\/jats:styled-content> and PMCA<\/jats:styled-content> were 80% and 42% respectively. The 5\u2010year survivals for appendiceal cancer with peritoneal cancer index (PCI<\/jats:styled-content>) <10, 10\u201320 and >20 were 60, 57 and 37% respectively (P<\/jats:italic> = 0.09). The 2\u2010 and 5\u2010year survivals for CRC<\/jats:styled-content> were 56 and 24% respectively. The 5\u2010year survivals for PCI<\/jats:styled-content> 0\u20135, 6\u201310, 11\u201315 and >15 were 59, 15, 7 and 0% respectively (P<\/jats:italic> = 0.000). The 5\u2010year survival for DMPM<\/jats:styled-content> with PCI<\/jats:styled-content> < 10, 10\u201320 and >20 were 100, 55 and 39% respectively (P<\/jats:italic> = 0.01).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>CRS<\/jats:styled-content> in combination with HIPEC<\/jats:styled-content> provides a chance of long\u2010term survival in selected cases of PC<\/jats:styled-content> when compared with systemic therapy alone.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.13152","type":"journal-article","created":{"date-parts":[[2015,7,14]],"date-time":"2015-07-14T15:52:37Z","timestamp":1436889157000},"page":"937-941","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: long\u2010term results at S<\/scp>t G<\/scp>eorge H<\/scp>ospital, A<\/scp>ustralia"],"prefix":"10.1111","volume":"86","author":[{"given":"Nayef","family":"Alzahrani","sequence":"first","affiliation":[{"name":"University of New South Wales Department of Surgery St George Hospital Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorgen S.","family":"Ferguson","sequence":"additional","affiliation":[{"name":"University of New South Wales Department of Surgery St George Hospital Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah J.","family":"Valle","sequence":"additional","affiliation":[{"name":"University of New South Wales Department of Surgery St George Hospital Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Winston","family":"Liauw","sequence":"additional","affiliation":[{"name":"University of New South Wales Department of Surgery St George Hospital Sydney New South Wales 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