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CHL\u2010induced anaphylaxis is poorly reported in surgical literature despite government warnings and growing recognition. The aim of this review is to increase awareness of <jats:styled-content style=\"fixed-case\">CHL<\/jats:styled-content>\u2010induced anaphylaxis in the surgical population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Literature review of <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>mbase, <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>edline, <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>ub<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ed and the <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ochrane library using \u2018anaphylaxis (and) chlorhexidine\u2019 search terms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010six articles were published on surgical patients suffering anaphylaxis to <jats:styled-content style=\"fixed-case\">CHL<\/jats:styled-content>. Within these, seven patients had two proven separate anaphylactic reactions and one had three separate proven anaphylactic reactions. The most commonly affected speciality was urology. The majority occurred during elective procedures. A history of atopy was surprisingly uncommon as was bronchospasm. Six patients required active chest compressions and 39.71% of patients had their surgical procedure abandoned. Unplanned intensive care admissions occurred in 27.94%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>In order to reduce abandoned procedures, unplanned intensive care unit admissions, morbidity and mortality associated with <jats:styled-content style=\"fixed-case\">CHL<\/jats:styled-content>\u2010induced anaphylaxis we recommend the following: rationalization of <jats:styled-content style=\"fixed-case\">CHL<\/jats:styled-content>\u2010containing products, greater vigilance regarding subtle symptoms of <jats:styled-content style=\"fixed-case\">CHL<\/jats:styled-content> allergy, appropriate investigation of these symptoms and a greater awareness of <jats:styled-content style=\"fixed-case\">CHL<\/jats:styled-content>\u2010containing products. Lastly, we outline the appropriate investigations and highlight the need for meticulous documentation in those who are <jats:styled-content style=\"fixed-case\">CHL<\/jats:styled-content> allergic.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.13269","type":"journal-article","created":{"date-parts":[[2015,9,12]],"date-time":"2015-09-12T03:38:43Z","timestamp":1442029123000},"page":"237-243","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["Chlorhexidine\u2010induced anaphylaxis in surgical patients: a review of the literature"],"prefix":"10.1111","volume":"86","author":[{"given":"Gary","family":"Sharp","sequence":"first","affiliation":[{"name":"Department of General Surgery Royal Prince Alfred Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Green","sequence":"additional","affiliation":[{"name":"Anaesthetic Allergy Service Royal North Shore Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Rose","sequence":"additional","affiliation":[{"name":"Anaesthetic Allergy Service Royal North Shore Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,9,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2004.00308.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.5301\/HIP.2011.8644"},{"key":"e_1_2_6_4_1","first-page":"5930","article-title":"Life\u2010threatening anaphylactic shock due to chlorhexidine on the central venous catheter: a case series","volume":"7","author":"Weng M","year":"2014","journal-title":"J. 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