{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T22:20:38Z","timestamp":1789770038593,"version":"4.0.1"},"reference-count":14,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2016,3,16]],"date-time":"2016-03-16T00:00:00Z","timestamp":1458086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2016,9]]},"abstract":"\n Background<\/jats:title>\n \n \n E<\/jats:italic>\n <\/jats:styled-content>\n nterobius vermicularis<\/jats:italic>\n is one of the most common parasitic infections of the gastrointestinal tract, and has been shown to infest up to 28% of children worldwide. The role of\n \n E<\/jats:italic>\n <\/jats:styled-content>\n . vermicularis<\/jats:italic>\n in acute appendicitis has previously been questioned, with some studies identifying infection as a precursor for inflammation of the appendix, with others refuting such a link.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A retrospective review was conducted of all appendices received for histological analysis at our unit from January 2002 to December 2011 (10\u2010year period), removed in the course of acute appendicectomy in children aged 3 to 15 years. Appendices were categorized by degree of inflammation and infestation with\n \n E<\/jats:italic>\n <\/jats:styled-content>\n . vermicularis<\/jats:italic>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Appendicectomy for clinical suspicion of acute appendicitis was performed in 2923 patients, 1694 (58%) male, median age 11.6 years.\n \n E<\/jats:italic>\n <\/jats:styled-content>\n . vermicularis<\/jats:italic>\n was present in 4% of appendices; 25% of which showed concurrent acute inflammation.\n \n E<\/jats:italic>\n <\/jats:styled-content>\n . vermicularis<\/jats:italic>\n infestation was more common in females (F : M 76% versus 24% of inflamed appendices and 66.7% versus 33.3% for non\u2010inflamed appendices). European individuals showed higher representation in the\n \n E<\/jats:italic>\n <\/jats:styled-content>\n . vermicularis<\/jats:italic>\n group than the total study population (79% versus 53% respectively).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n \n E<\/jats:italic>\n <\/jats:styled-content>\n . vermicularis<\/jats:italic>\n was found to be more common in females and those of European descent. Seventy\u2010seven percent of patients with\n \n E<\/jats:italic>\n <\/jats:styled-content>\n . vermicularis<\/jats:italic>\n did not have concurrent acute inflammation of the appendix on histological examination. The question remains as to whether infestation is protective of inflammation or whether infestation causes appendiceal colic and subsequent appendicectomy of a non\u2010inflamed appendix, thereby protective of the morbidity of acute appendicitis.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ans.13464","type":"journal-article","created":{"date-parts":[[2016,3,18]],"date-time":"2016-03-18T22:09:25Z","timestamp":1458338965000},"page":"717-719","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Enterobius vermicularis<\/i>\n and its role in paediatric appendicitis: protection or predisposition?"],"prefix":"10.1111","volume":"86","author":[{"given":"Shareena","family":"Lala","sequence":"first","affiliation":[{"name":"Department of Paediatric Surgery and Urology Starship Children's Health Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vipul","family":"Upadhyay","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery and Urology Starship Children's Health Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,3,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365529109025051"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e318258cdb5"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.3347\/kjp.2011.49.2.183"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-004-1151-5"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2010.06.007"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365520802624227"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-007-0735-0"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.1994.tb02059.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"crossref","first-page":"E523","DOI":"10.1177\/000313481207801211","article-title":"Enterobius vermicularis: a cause of acute appendicitis in children","volume":"78","author":"Maki AC","year":"2012","journal-title":"Am. Surg."},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.5152\/tpd.2012.09"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2013-202962"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800740834"},{"key":"e_1_2_6_14_1","unstructured":"Dermnet NZ.Dermnet New Zealand Trust updated 29 Dec2013. [Cited 26 Sep 2015.] Available from URL:http:\/\/dermnetnz.org\/arthropods\/pinworm.html"},{"key":"e_1_2_6_15_1","unstructured":"Centers for Disease Control and Prevention.Atlanta USA: CDC Global Health \u2013 Division of Parasitic Diseases and Malaria updated 19 July2013. [Cited 26 Sep 2015.] Available from URL:http:\/\/www.cdc.gov\/parasites\/pinworm\/treatment.html"}],"container-title":["ANZ Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fans.13464","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fans.13464","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.13464","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T11:33:20Z","timestamp":1695468800000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ans.13464"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,16]]},"references-count":14,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.1111\/ans.13464"],"URL":"https:\/\/doi.org\/10.1111\/ans.13464","archive":["Portico"],"relation":{},"ISSN":["1445-1433","1445-2197"],"issn-type":[{"value":"1445-1433","type":"print"},{"value":"1445-2197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,16]]},"assertion":[{"value":"2015-12-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-03-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}