{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T03:06:19Z","timestamp":1773284779962,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,3,31]],"date-time":"2016-03-31T00:00:00Z","timestamp":1459382400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Hepatic resection is standard treatment for liver metastases from colorectal and neuroendocrine cancers as well as primary biliary and hepatic carcinomas. The role of hepatic resection in patients with non\u2010colorectal non\u2010endocrine liver metastases (<jats:styled-content style=\"fixed-case\">NCNELM<\/jats:styled-content>) is less defined. Overall survival in this group of patients is poor with few patients surviving beyond two years, even with modern chemotherapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective database of all liver resections performed by a single surgeon (<jats:styled-content style=\"fixed-case\">KSH<\/jats:styled-content>) from January 2007 to December 2014 was maintained. Patient demographics, surgical and pathological data were collected prospectively; survival data were updated retrospectively. Patients were grouped according to pathology and analysis was performed using <jats:styled-content style=\"fixed-case\">SPSS<\/jats:styled-content> (version 21).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 48 patients underwent hepatic resection for <jats:styled-content style=\"fixed-case\">NCNELM<\/jats:styled-content>, of which 18 were major resections. Pathologies encountered included sarcoma in 8\/48, both breast and ovarian in 6\/48 each and renal cell carcinoma and melanoma, each representing 5\/48. A result of 38\/48 patients undertook chemotherapy prior to surgery. R0 margin was achieved in 96%. Seven patients suffered complications from surgery and one peri\u2010operative mortality. Overall survival at 1, 3 and 5 years was 93%, 83% and 61%, respectively. Forty\u2010four percent of patients developed disease recurrence, 29% at distant sites.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Hepatic resection can be achieved safely for <jats:styled-content style=\"fixed-case\">NCNELM<\/jats:styled-content>. Patient selection is key, along with a standardized surgical and anaesthetic technique. Patients should be rigorously investigated to exclude disseminated disease and multidisciplinary discussion must take place prior to surgery. Patients with <jats:styled-content style=\"fixed-case\">NCNELM<\/jats:styled-content> should not routinely be excluded from liver resection and selected patients may benefit from resection.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.13470","type":"journal-article","created":{"date-parts":[[2016,4,2]],"date-time":"2016-04-02T17:00:48Z","timestamp":1459616448000},"page":"810-814","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Hepatic resection of non\u2010colorectal non\u2010endocrine liver metastases"],"prefix":"10.1111","volume":"87","author":[{"given":"Robert C.","family":"Gandy","sequence":"first","affiliation":[{"name":"The Prince of Wales Hospital  Sydney, New South Wales Australia"},{"name":"The University of New South Wales  Sydney, New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul A.","family":"Bergamin","sequence":"additional","affiliation":[{"name":"The Prince of Wales Hospital  Sydney, New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koroush S.","family":"Haghighi","sequence":"additional","affiliation":[{"name":"The Prince of Wales Hospital  Sydney, New South Wales Australia"},{"name":"The University of New South Wales  Sydney, New South Wales Australia"},{"name":"St Vincent's Hospital  Sydney, New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,3,31]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"283","article-title":"Survival after liver resection in metastatic colorectal cancer. 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