{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T02:30:00Z","timestamp":1790994600249,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"1-2","license":[{"start":{"date-parts":[[2016,4,21]],"date-time":"2016-04-21T00:00:00Z","timestamp":1461196800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>This study assessed and compared the morbidity of nodal dissection in the axilla and groin including sentinel lymph node biopsy (<jats:styled-content style=\"fixed-case\">SLNB<\/jats:styled-content>), completion lymph node dissection for a positive <jats:styled-content style=\"fixed-case\">SLNB<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">CLND<\/jats:styled-content>) and therapeutic lymph node dissection (<jats:styled-content style=\"fixed-case\">TLND<\/jats:styled-content>) with and without adjuvant radiotherapy (<jats:styled-content style=\"fixed-case\">RT<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who had nodal dissection in the axilla or groin for cutaneous melanoma over an 18\u2010year period (1995\u20132013) were prospectively documented on a database. The median follow\u2010up was nearly 3\u2009years. Early complications and clinically relevant lymphoedema were retrospectively analysed to assess the incidence and differences between the region and type of nodal surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Included were 1521 patients following nodal dissection in the axilla (916 patients) and groin (605 patients). Less early complications occurred following <jats:styled-content style=\"fixed-case\">SLNB<\/jats:styled-content> in the axilla compared with the groin (5% versus 14%, <jats:italic>P<\/jats:italic>\u2009=\u20090.0001). Early complications were similar for <jats:styled-content style=\"fixed-case\">CLND<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">TLND<\/jats:styled-content> in the groin (49% versus 43%, <jats:italic>P<\/jats:italic>\u2009=\u20090.879) and axilla (28% versus 33%, <jats:italic>P<\/jats:italic>\u2009=\u20090.607). Moderate to severe lymphoedema rates were similar following axillary <jats:styled-content style=\"fixed-case\">SLNB<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CLND<\/jats:styled-content> (6% versus 8%, <jats:italic>P<\/jats:italic>\u2009=\u20090.407). The lymphoedema rate for groin <jats:styled-content style=\"fixed-case\">SLNB<\/jats:styled-content> was lower than <jats:styled-content style=\"fixed-case\">CLND<\/jats:styled-content> (10% versus 20%, <jats:italic>P<\/jats:italic>\u2009=\u20090.063). No significant difference in lymphoedema rates followed <jats:styled-content style=\"fixed-case\">CLND<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">TLND<\/jats:styled-content> in each region. Following <jats:styled-content style=\"fixed-case\">TLND<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">RT<\/jats:styled-content> increased lymphoedema rates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Morbidity may occur following <jats:styled-content style=\"fixed-case\">SLNB<\/jats:styled-content> with the groin having a higher rate of early complications and lymphoedema compared with the axilla. The morbidity following <jats:styled-content style=\"fixed-case\">CLND<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">TLND<\/jats:styled-content> were similar. Lymphoedema rates were increased following <jats:styled-content style=\"fixed-case\">RT<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.13526","type":"journal-article","created":{"date-parts":[[2016,4,22]],"date-time":"2016-04-22T07:23:54Z","timestamp":1461309834000},"page":"44-48","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Assessment of morbidity following regional nodal dissection in the axilla and groin for metastatic melanoma"],"prefix":"10.1111","volume":"87","author":[{"given":"Jane E.","family":"Theodore","sequence":"first","affiliation":[{"name":"The Queensland Melanoma Project Princess Alexandra Hospital  Brisbane Queensland Australia"},{"name":"The University of Queensland Mater Health Services  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam J.","family":"Frankel","sequence":"additional","affiliation":[{"name":"The Queensland Melanoma Project Princess Alexandra Hospital  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janine M.","family":"Thomas","sequence":"additional","affiliation":[{"name":"The Queensland Melanoma Project Princess Alexandra Hospital  Brisbane Queensland Australia"},{"name":"Mater Research Institute Mater Health Services  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew P.","family":"Barbour","sequence":"additional","affiliation":[{"name":"The Queensland Melanoma Project Princess Alexandra Hospital  Brisbane Queensland Australia"},{"name":"Princess Alexandra Hospital The University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard J.","family":"Bayley","sequence":"additional","affiliation":[{"name":"The Queensland Melanoma Project Princess Alexandra Hospital  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher P.","family":"Allan","sequence":"additional","affiliation":[{"name":"The Queensland Melanoma Project Princess Alexandra Hospital  Brisbane Queensland Australia"},{"name":"The University of Queensland Mater Health Services  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Wagels","sequence":"additional","affiliation":[{"name":"The Queensland Melanoma Project Princess Alexandra Hospital  Brisbane Queensland Australia"},{"name":"Princess Alexandra Hospital The University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. 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