{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T17:52:10Z","timestamp":1703613130382},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,8,3]],"date-time":"2016-08-03T00:00:00Z","timestamp":1470182400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Liver resections for non\u2010colorectal non\u2010neuroendocrine liver metastases (<jats:styled-content style=\"fixed-case\">NCNELM<\/jats:styled-content>) are gaining popularity. This study examines the outcomes of liver resections in patients with <jats:styled-content style=\"fixed-case\">NCNELM<\/jats:styled-content> in an Australian hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A database search identified 21 attempted liver resections on 20 patients (12 men, eight women, mean age: 63.1) from 1998 to 2013. A retrospective analysis considered patient demographics and primary malignancy details. Complication rates were compared to those for colorectal metastases at the same institution. Kaplan\u2013Meier curves were used to plot overall survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Complete resection was achieved in 16 of the 21 operations with 13 cases having proven metastases (three cases were benign lesions on final histology). Primary cancers were gastric (<jats:italic>n<\/jats:italic>\u2009=\u20094), gall bladder\/bile duct (<jats:italic>n<\/jats:italic>\u2009=\u20093), renal (<jats:italic>n<\/jats:italic>\u2009=\u20093), soft tissue sarcoma (<jats:italic>n<\/jats:italic>\u2009=\u20093), melanoma (<jats:italic>n<\/jats:italic>\u2009=\u20092), pancreatic (<jats:italic>n<\/jats:italic>\u2009=\u20092), anal (<jats:italic>n<\/jats:italic>\u2009=\u20092), breast (<jats:italic>n<\/jats:italic>\u2009=\u20091) and unknown (<jats:italic>n<\/jats:italic>\u2009=\u20091). Primary histology types were adenocarcinoma (<jats:italic>n<\/jats:italic>\u2009=\u200910), sarcoma (<jats:italic>n<\/jats:italic>\u2009=\u20093), renal cell (<jats:italic>n<\/jats:italic>\u2009=\u20093), squamous cell (<jats:italic>n<\/jats:italic>\u2009=\u20092), melanoma (<jats:italic>n<\/jats:italic>\u2009=\u20092) and gastrointestinal stromal tumour (<jats:italic>n<\/jats:italic>\u2009=\u20091). There was no peri\u2010operative mortality. Significant post\u2010operative complications (Clavien\u2013Dindo Grade <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> or more) occurred in six patients (28.5%). Overall survival at 2 and 5 years was 46.2% and 30.8%, respectively, for all 21 cases of attempted resection, and 51.9% and 34.6%, respectively, for the 13 cases of complete resection of malignant metastases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study produced comparable 5\u2010year survival rates to those reported after liver resection for colorectal metastases and in other studies on <jats:styled-content style=\"fixed-case\">NCNELM<\/jats:styled-content>. Complication rates were comparable to those for colorectal liver metastasis resection at the same institution.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.13700","type":"journal-article","created":{"date-parts":[[2016,8,4]],"date-time":"2016-08-04T01:23:47Z","timestamp":1470273827000},"update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Liver resection for non\u2010colorectal non\u2010neuroendocrine metastases"],"prefix":"10.1111","volume":"88","author":[{"given":"Nicholas A. 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