{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:44:10Z","timestamp":1787013850603,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,9,6]],"date-time":"2016-09-06T00:00:00Z","timestamp":1473120000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2017,5]]},"abstract":"\n Background<\/jats:title>\n \n Recent data suggest that laparoscopic appendicectomy (\n LA<\/jats:styled-content>\n ) in pregnancy is associated with higher rates of foetal loss when compared to open appendicectomy (\n OA<\/jats:styled-content>\n ). However, the influence of gestational age and maternal age, both recognized risk factors for foetal loss, was not assessed.\n <\/jats:p>\n <\/jats:sec>\n \n Method<\/jats:title>\n This was a multicentre retrospective review of all pregnant patients who underwent appendicectomy for suspected appendicitis from 2000 to 2012 across seven hospitals in Australia. Perioperative data and foetal outcome were evaluated.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Data on 218 patients from the seven hospitals were included in the analysis. A total of 125 underwent\n LA<\/jats:styled-content>\n and 93\n OA<\/jats:styled-content>\n . There were seven (5.6%) foetal losses in the\n LA<\/jats:styled-content>\n group, six of which occurred in the first trimester, and none in the\n OA<\/jats:styled-content>\n group. After matching using propensity scores, the estimated risk difference was 5.1% (95% confidence interval (\n CI<\/jats:styled-content>\n ): 1.4%, 9.8%). First trimester patients were more likely to undergo\n LA<\/jats:styled-content>\n (84%), while those in the third were more likely to undergo\n OA<\/jats:styled-content>\n (85%). Preterm delivery rates (6.8%\n LA<\/jats:styled-content>\n versus 8.6%\n OA<\/jats:styled-content>\n ;\n CI<\/jats:styled-content>\n : \u221212.6%, 5.3%) and hospital length of stay (3.7 days\n LA<\/jats:styled-content>\n versus 4.5 days\n OA<\/jats:styled-content>\n ;\n CI<\/jats:styled-content>\n : \u22121.3, 0.2 days) were similar.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n This is the largest published dataset investigating the outcome after\n LA<\/jats:styled-content>\n versus\n OA<\/jats:styled-content>\n while adjusting for gestational and maternal age.\n OA<\/jats:styled-content>\n appears to be a safer approach for pregnant patients with suspected appendicitis.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ans.13750","type":"journal-article","created":{"date-parts":[[2016,9,6]],"date-time":"2016-09-06T19:38:13Z","timestamp":1473190693000},"page":"334-338","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Laparoscopic or open appendicectomy for suspected appendicitis in pregnancy and evaluation of foetal outcome in Australia"],"prefix":"10.1111","volume":"87","author":[{"given":"Nicole N.","family":"Winter","sequence":"first","affiliation":[{"name":"Department of Surgery Barwon Health Geelong Victoria Australia"},{"name":"Department of Specialist General Surgery The Royal Melbourne Hospital Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glenn D.","family":"Guest","sequence":"additional","affiliation":[{"name":"Department of Surgery Barwon Health Geelong Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Bozin","sequence":"additional","affiliation":[{"name":"Department of Specialist General Surgery The Royal Melbourne Hospital Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin N.","family":"Thomson","sequence":"additional","affiliation":[{"name":"Department of Specialist General Surgery The Royal Melbourne Hospital Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. 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M.","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Surgery Royal Brisbane and Women's Hospital Herston Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Clark","sequence":"additional","affiliation":[{"name":"Department of Surgery Royal Brisbane and Women's Hospital Herston Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jurstine","family":"Daruwalla","sequence":"additional","affiliation":[{"name":"Department of Surgery, Austin Health The University of Melbourne Heidelberg Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijayaragavan","family":"Muralidharan","sequence":"additional","affiliation":[{"name":"Department of Surgery, Austin Health The University of Melbourne Heidelberg Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neeha","family":"Najan","sequence":"additional","affiliation":[{"name":"Department of Surgery Western Health Footscray Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meron E.","family":"Pitcher","sequence":"additional","affiliation":[{"name":"Department of Surgery Western Health Footscray Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina","family":"Vilhelm","sequence":"additional","affiliation":[{"name":"Department of Surgery Nepean Hospital Kingswood New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Cox","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Sydney Clinical School, Nepean Hospital Kingswood New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven E.","family":"Lane","sequence":"additional","affiliation":[{"name":"Biostatistics Unit Barwon Health Geelong Victoria Australia"},{"name":"School of Medicine Deakin University Geelong Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Watters","sequence":"additional","affiliation":[{"name":"Department of Surgery, Barwon Health Deakin University Geelong Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,9,6]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"371","article-title":"The effect of nonobstetric operation during pregnancy","volume":"177","author":"Kort B","year":"1993","journal-title":"Surg. 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