{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T12:10:59Z","timestamp":1780920659217,"version":"3.54.1"},"reference-count":27,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2016,9,29]],"date-time":"2016-09-29T00:00:00Z","timestamp":1475107200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2016,9,29]],"date-time":"2016-09-29T00:00:00Z","timestamp":1475107200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      The aim of this analysis was to compare the advantages of the anal fistula plug (\n                      <jats:styled-content style=\"fixed-case\">AFP<\/jats:styled-content>\n                      ) with the mucosa advancement flap (\n                      <jats:styled-content style=\"fixed-case\">MAF<\/jats:styled-content>\n                      ) for complex anal fistulas.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Comparative studies of the efficacy of\n                      <jats:styled-content style=\"fixed-case\">AFP<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">MAF<\/jats:styled-content>\n                      were included. Two independent reviewers selected articles for inclusion. After information collection, a meta\u2010analysis was performed using data on overall healing rates, complications, incontinences and recurrences. The quality of postoperative life and cost were also included with the clinical results.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Ten studies included 778 patients who were divided into\n                      <jats:styled-content style=\"fixed-case\">AFP<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">MAF<\/jats:styled-content>\n                      groups in this meta\u2010analysis. During the follow\u2010up period, no significant difference in healing rates, complications and recurrences were found (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.55,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.78 and\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.23, respectively). The incontinence rate of\n                      <jats:styled-content style=\"fixed-case\">AFP<\/jats:styled-content>\n                      was lower than that of\n                      <jats:styled-content style=\"fixed-case\">MAF<\/jats:styled-content>\n                      (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.04). The postoperative quality of life of\n                      <jats:styled-content style=\"fixed-case\">AFP<\/jats:styled-content>\n                      patients was superior to that of\n                      <jats:styled-content style=\"fixed-case\">MAF<\/jats:styled-content>\n                      patients. The\n                      <jats:styled-content style=\"fixed-case\">AFP<\/jats:styled-content>\n                      patients had less persistent pain of a shorter duration and shortened healing time and hospital stay. The treatment cost of\n                      <jats:styled-content style=\"fixed-case\">AFP<\/jats:styled-content>\n                      patient was lower than that of\n                      <jats:styled-content style=\"fixed-case\">MAF<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Compared to the\n                      <jats:styled-content style=\"fixed-case\">MAF<\/jats:styled-content>\n                      procedure, the\n                      <jats:styled-content style=\"fixed-case\">AFP<\/jats:styled-content>\n                      procedure has some advantages for complex anal fistulas, but more and large randomized clinical trials comparing the two procedures for fistula management need to be conducted.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ans.13751","type":"journal-article","created":{"date-parts":[[2016,9,29]],"date-time":"2016-09-29T01:53:06Z","timestamp":1475113986000},"page":"978-982","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Comparison of an anal fistula plug and mucosa advancement flap for complex anal fistulas: a meta\u2010analysis"],"prefix":"10.1111","volume":"86","author":[{"given":"Yansong","family":"Xu","sequence":"first","affiliation":[{"name":"Emergency Department The First Affiliated Hospital of Guangxi Medical University  Nanning, Guangxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weizhong","family":"Tang","sequence":"additional","affiliation":[{"name":"Colorectal and Anal Department The First Affiliated Hospital of Guangxi Medical University  Nanning, Guangxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,9,29]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e31819a5c52"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-007-0334-7"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v17.i28.3286"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.2000.01582.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-006-0172-z"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-008-9242-3"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-005-0288-1"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e318239d1e4"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.14.4791"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2009.02087.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v16.i26.3279"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6613"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e318206043e"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2008.12.013"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e31819756ac"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2010.05540.x"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cursur.2006.07.005"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e31819d473f"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2009.05.018"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12888"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2482-8-11"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01648418"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800810947"},{"key":"e_1_2_5_25_1","first-page":"1584","article-title":"Anal fistula plug in high fistula\u2010in\u2010ano: an early Saudi experience","volume":"52","author":"Zubaidi A","year":"2009","journal-title":"Dis. 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