{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T06:23:40Z","timestamp":1760077420011},"reference-count":19,"publisher":"Wiley","issue":"1-2","license":[{"start":{"date-parts":[[2016,10,18]],"date-time":"2016-10-18T00:00:00Z","timestamp":1476748800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004329","name":"Genzyme","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004329","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The American Thyroid Association (<jats:styled-content style=\"fixed-case\">ATA<\/jats:styled-content>) management guidelines for thyroid cancer were revised in 2009. The aim of this study was to determine if management of thyroid cancer in our institution has changed in accordance with the introduction of the revised <jats:styled-content style=\"fixed-case\">ATA<\/jats:styled-content> guidelines (<jats:styled-content style=\"fixed-case\">ATA<jats:sup>2009<\/jats:sup>\n<\/jats:styled-content>), and to compare the characteristics and management of thyroid cancer in a Melbourne endocrine surgery unit over a 7\u2010year period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients treated by the Monash University Endocrine Surgery Unit for thyroid cancer between 2007 and 2013 were divided into two groups \u2013 the pre\u2010<jats:styled-content style=\"fixed-case\">ATA<jats:sup>2009<\/jats:sup>\n<\/jats:styled-content> group (2007\u20132010) and the post\u2010<jats:styled-content style=\"fixed-case\">ATA<jats:sup>2009<\/jats:sup>\n<\/jats:styled-content> group (2011\u20132013). Comparisons were made of the demographics, cytology, pathology, surgical outcome and adjuvant therapy using <jats:italic>t<\/jats:italic>\u2010test and chi\u2010squared tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 333 patients in the pre\u2010<jats:styled-content style=\"fixed-case\">ATA<jats:sup>2009<\/jats:sup>\n<\/jats:styled-content> group and 342 patients in the post\u2010<jats:styled-content style=\"fixed-case\">ATA<jats:sup>2009<\/jats:sup>\n<\/jats:styled-content> group. Fewer non\u2010diagnostic fine\u2010needle aspiration cytology results were identified in the post\u2010<jats:styled-content style=\"fixed-case\">ATA<jats:sup>2009<\/jats:sup>\n<\/jats:styled-content> group (4% versus 0.9%; <jats:italic>P<\/jats:italic>\u2009=\u20090.01), while the rates of other fine\u2010needle aspiration cytology categories were similar. There was a reduction in the use of radioactive iodine ablation in the post\u2010<jats:styled-content style=\"fixed-case\">ATA<jats:sup>2009<\/jats:sup>\n<\/jats:styled-content> group, both in the proportion of patients being treated (66% versus 48%; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and the dosages used (mean 96 <jats:styled-content style=\"fixed-case\">mCi<\/jats:styled-content> versus 80 <jats:styled-content style=\"fixed-case\">mCi<\/jats:styled-content>; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01), despite similar tumour size in both groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The key changes in practice thought to be attributable to the 2009 revised <jats:styled-content style=\"fixed-case\">ATA<\/jats:styled-content> guidelines were the reduction in the use and dosage of radioactive iodine in the management of differentiated thyroid cancer.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.13792","type":"journal-article","created":{"date-parts":[[2016,10,19]],"date-time":"2016-10-19T02:33:44Z","timestamp":1476844424000},"page":"38-42","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Temporal analysis of thyroid cancer management in a Melbourne tertiary centre"],"prefix":"10.1111","volume":"89","author":[{"given":"James C.","family":"Lee","sequence":"first","affiliation":[{"name":"Monash University Endocrine Surgery Unit The Alfred Hospital  Melbourne Victoria Australia"},{"name":"Department of Surgery Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula","family":"Chang","sequence":"additional","affiliation":[{"name":"Monash University Endocrine Surgery Unit The Alfred Hospital  Melbourne Victoria 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