{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T09:26:04Z","timestamp":1775121964761,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,7,20]],"date-time":"2017-07-20T00:00:00Z","timestamp":1500508800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The acellular dermal matrix (Flex <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content>) (<jats:styled-content style=\"fixed-case\">FHD<\/jats:styled-content>) became available for use in Western Australia in 2014 to aid prosthetic breast reconstruction and this descriptive study aims to review and discuss a single institution's experience since its introduction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>By retrospective case note, review data were collected for all patients who underwent prosthetic breast reconstruction with the aid of <jats:styled-content style=\"fixed-case\">FHD<\/jats:styled-content> between January 2014 and August 2015 in our institution. Data on basic demographic parameters, risk factors, surgery\u2010related factors, post\u2010operative factors and follow\u2010up information were collected. All complications were recorded and described in detail.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">FHD<\/jats:styled-content> was used in 42 breast reconstructions in 26 patients. Procedure\u2010related complications were seen in 26% (<jats:italic>n<\/jats:italic>\u2009=\u200911) of cases. A major complication requiring return to theatre was seen in 11% (<jats:italic>n<\/jats:italic>\u2009=\u20095) of cases. Cellulitis of the reconstructed breast (red breast syndrome) was seen in 16.67% (<jats:italic>n<\/jats:italic>\u2009=\u20097) cases. Overall implant loss was 2.4% (<jats:italic>n<\/jats:italic>\u2009=\u20091). Of the six possible risk factors for any complication, only current smoking was found to increase the risk of complications (odds ratio\u2009=\u20099.667, 95% confidence interval\u2009=\u20091.429\u201365.377).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">FHD<\/jats:styled-content> is associated with a relatively high overall complication rate. Use of this optional expensive material has to be carefully selected balancing its perceived advantages against this possible risk. The red breast syndrome merits further studies considering its frequent occurrence with <jats:styled-content style=\"fixed-case\">FHD<\/jats:styled-content> use.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.13857","type":"journal-article","created":{"date-parts":[[2017,7,20]],"date-time":"2017-07-20T10:15:21Z","timestamp":1500545721000},"page":"369-373","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Pre\u2010hydrated sterile acellular dermal matrix allograft in breast reconstruction: review of a single unit's experience"],"prefix":"10.1111","volume":"88","author":[{"given":"Justin","family":"James","sequence":"first","affiliation":[{"name":"Department of General Surgery Royal Perth Hospital  Perth Western Australia Australia"},{"name":"Faculty of Medicine, Nursing and Health Sciences Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brigid","family":"Corrigan","sequence":"additional","affiliation":[{"name":"Department of General Surgery Royal Perth Hospital  Perth Western Australia Australia"},{"name":"Department of Plastic and Reconstructive Surgery Fiona Stanley Hospital  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christobel","family":"Saunders","sequence":"additional","affiliation":[{"name":"Department of General Surgery Royal Perth Hospital  Perth Western Australia Australia"},{"name":"School of Surgery, The University of Western Australia, Harry Perkins Institute of Medical Research Fiona Stanley Hospital  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,7,20]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"National Comprehensive Cancer Network.NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) Breast Cancer.Version 3. 2015 edn. 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