{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:21:18Z","timestamp":1740126078883,"version":"3.37.3"},"reference-count":28,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,5,16]],"date-time":"2017-05-16T00:00:00Z","timestamp":1494892800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Royal Adelaide Hospital Research Infrastructure Block Grant"},{"name":"Royal Adelaide Hospital Research Fund - Sarcoma Research Fund"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Sarcomas affecting the head and neck often require complex management due to the combination of anatomic, aesthetic and oncological considerations. The incidence and patterns of presentation are poorly understood and have not been reviewed in the Australian population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This study sourced incidence and demographic data from the National Cancer Registry at the Australian Institute of Health and Welfare for the years 1982\u20132009 (corresponding to 97.3% of the Australian population). All cases of sarcoma, according to <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content>\u2010O\u20103 classification ((International Classification of Diseases for Oncology, 3rd edition), were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 3911 new cases of sarcoma affecting the head and neck were recorded during the period 1982\u20132009, including 1383, 2106 and 442 cases arising from skin, soft tissue and bone, respectively. The annual incidence rate of sarcomas affecting the head and neck was 1.59 per 100 000 population. The incidence of head and neck sarcoma rose substantially in older age groups (age 65 years and above) and was most common in male patients (69%). Malignant fibrous histiocytoma (<jats:styled-content style=\"fixed-case\">MFH<\/jats:styled-content>) was the most common pathology. There was an increase in incidence in skin\u2010origin sarcoma in the head and neck, particularly affecting elderly males.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The incidence of head and neck sarcoma in Australia is higher than that reported for an equivalent European population. The increase in <jats:styled-content style=\"fixed-case\">MFH<\/jats:styled-content> arising from the skin in elderly male patients mirrors the patterns of common cutaneous malignancy, particularly melanoma, suggesting that ultraviolet radiation is an epidemiological factor. Management of head and neck sarcoma is complex and best managed in a specialist multidisciplinary environment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.14018","type":"journal-article","created":{"date-parts":[[2017,5,17]],"date-time":"2017-05-17T00:56:46Z","timestamp":1494982606000},"page":"901-906","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Patterns of head and neck sarcoma in Australia"],"prefix":"10.1111","volume":"88","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2787-1562","authenticated-orcid":false,"given":"Roger H.","family":"Woods","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Department of Plastic Surgery Women's and Children's Hospital  North Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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