{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T05:55:11Z","timestamp":1771912511854,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,5,16]],"date-time":"2017-05-16T00:00:00Z","timestamp":1494892800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2018,5]]},"abstract":"Background<\/jats:title>The occurrence of post\u2010operative pancreatic fistula (POPF<\/jats:styled-content>) after pancreaticoduodenectomy is a challenging issue. The aim was to identify variables on preoperative computed tomography (CT<\/jats:styled-content>) scan, useful to predict clinically significant POPF<\/jats:styled-content> (grades B\u2013C) after pancreaticoduodenectomy.<\/jats:p><\/jats:sec>Methods<\/jats:title>Patients presented POPF<\/jats:styled-content> after pancreaticoduodenectomy were included from two tertiary referral centres. B\/W ratio was defined by ratio of pancreas body thickness (B) to main pancreatic duct (W). The predictive parameters of POPF<\/jats:styled-content> on CT<\/jats:styled-content> scan were assessed with a receiving operator characteristics (ROC<\/jats:styled-content>) curve and intrinsic characteristics.<\/jats:p><\/jats:sec>Results<\/jats:title>Between 2010 and 2013, 186 patients who underwent pancreaticoduodenectomy were included. POPF<\/jats:styled-content> occurred in 25% of them, and was clinically significant in 13%. After univariate analysis, endocrine tumours (P<\/jats:italic>\u2009=\u20090.03), main pancreatic duct size (P<\/jats:italic>\u2009<\u20090.01) and B\/W ratio (P<\/jats:italic>\u2009=\u20090.04) were significantly associated with POPF<\/jats:styled-content>. ROC<\/jats:styled-content> curve showed a greater area under curve for B\/W ratio (0.68) than for main pancreatic duct size (0.33). A 3.8 threshold displayed 80 and 51% for sensibility and specificity, respectively, and a negative predictive value of 94%. A B\/W ratio >3.8 increased the rates of post\u2010operative haemorrhage (odds ratio\u2009=\u20094.3 (1.4\u201313.2), P<\/jats:italic>\u2009=\u20090.01), and reintervention (odds ratio\u2009=\u20093.4 (1.2\u20139.6), P<\/jats:italic>\u2009=\u20090.02).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>B\/W ratio superior to 3.8 assessed on preoperative CT<\/jats:styled-content> scan may be an easy tool to predict clinically significant POPF<\/jats:styled-content> after pancreaticoduodenectomy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.14048","type":"journal-article","created":{"date-parts":[[2017,5,17]],"date-time":"2017-05-17T00:58:45Z","timestamp":1494982725000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Predict pancreatic fistula after pancreaticoduodenectomy: ratio body thickness\/main 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