{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:17:35Z","timestamp":1782778655399,"version":"3.54.5"},"reference-count":35,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,12,21]],"date-time":"2017-12-21T00:00:00Z","timestamp":1513814400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Lymphocele development following renal transplantation is a significant adverse event. It may cause acute graft dysfunction or venous obstruction. There are no consistent risk factors reported in literature. Perioperative fluid balance may lead to increased lymphocele formation and has never been studied. We aimed to analyse incidence and risk factors for lymphocele formation. We hypothesized that overhydration in perioperative period is a risk factor.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analysed 250 consecutive renal transplant recipients from 2006 to 2014. All recipients had undergone protocol screening by computerized tomography and ultrasound scan at 3 months post\u2010transplant. We analysed risk factors for lymphocele formation. Comparisons between lymphocele and no\u2010lymphocele groups were made with binary logistic regression analyses. Renal function was compared between treated, untreated and no\u2010lymphocele groups with linear regression analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010one of 250 (12.4%) transplant recipients developed lymphocele. Fourteen of 31 (45.4%) recipients required intervention due to symptoms (venous obstruction being the most common). Surgical drainage was done in all symptomatic patients (11 laparoscopic and three open). Two of 11 (18%) recipients had recurrence after laparoscopic drainage. There were no significant differences in risk factors between the lymphocele and no\u2010lymphocele groups. Renal function was comparable between no\u2010lymphocele and treated lymphocele groups. Untreated lymphocele group trended towards better graft function at 1 year (<jats:italic>P<\/jats:italic> = 0.051).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Post\u2010transplant lymphocele developed one in eight transplant recipients and tended to occur in those with good renal function. Around half of the recipients with lymphocele required intervention with good recovery of long\u2010term renal function. No risk factor for lymphocele development was established.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.14343","type":"journal-article","created":{"date-parts":[[2018,6,4]],"date-time":"2018-06-04T17:08:42Z","timestamp":1528132122000},"page":"597-602","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Functional significance and risk factors for lymphocele formation after renal transplantation"],"prefix":"10.1111","volume":"88","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3956-0334","authenticated-orcid":false,"given":"Munish K.","family":"Heer","sequence":"first","affiliation":[{"name":"Newcastle Transplant Unit John Hunter Hospital  Newcastle New South Wales Australia"},{"name":"The University of Newcastle  Newcastle New South Wales Australia"},{"name":"Hunter Transplant Research Foundation  Newcastle New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Clark","sequence":"additional","affiliation":[{"name":"Newcastle Transplant Unit John Hunter Hospital  Newcastle New South Wales Australia"},{"name":"The University of Newcastle  Newcastle New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul R.","family":"Trevillian","sequence":"additional","affiliation":[{"name":"Newcastle Transplant Unit John Hunter Hospital  Newcastle New South Wales Australia"},{"name":"The University of Newcastle  Newcastle New South Wales Australia"},{"name":"Hunter Transplant Research Foundation  Newcastle New South Wales Australia"},{"name":"Hunter Medical Research Institute  Newcastle New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Sprott","sequence":"additional","affiliation":[{"name":"Newcastle Transplant Unit John Hunter Hospital  Newcastle New South Wales Australia"},{"name":"The University of Newcastle  Newcastle New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerrin","family":"Palazzi","sequence":"additional","affiliation":[{"name":"Hunter Medical Research Institute  Newcastle New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian D.","family":"Hibberd","sequence":"additional","affiliation":[{"name":"Newcastle Transplant Unit John Hunter Hospital  Newcastle New South Wales Australia"},{"name":"The University of Newcastle  Newcastle New South Wales Australia"},{"name":"Hunter Transplant Research Foundation  Newcastle New South Wales Australia"},{"name":"Hunter Medical Research Institute  Newcastle New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,12,21]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"88","article-title":"Lymphocele following renal transplantation","volume":"47","author":"Baumgartner D","year":"1976","journal-title":"Chirurg"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2011.08.079"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000289573"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.11622\/smedj.2013104"},{"key":"e_1_2_7_6_1","first-page":"178","article-title":"Clinical and experimental studies on the so\u2010called lymphocyst which develops after radical hysterectomy in cancer of the uterine cervix","volume":"2","author":"Mori N","year":"1955","journal-title":"J. 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