{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:18:12Z","timestamp":1762431492748,"version":"3.40.5"},"reference-count":34,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,5,15]],"date-time":"2018-05-15T00:00:00Z","timestamp":1526342400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Neurolytic celiac plexus block (NCPB) is an effective method of palliative pain control. The purpose of this study was to evaluate the feasibility and effectiveness of the laparoscopic NCPB versus open approach.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eight patients (Group A) underwent diagnostic laparoscopy which revealed an inoperable pancreatic cancer. Forty millilitres of solution (20\u2009mL of 95% ethanol mixed with 20\u2009mL of xylocaine) was injected into either side of para\u2010aortic soft tissue. The same solution was injected in 10 patients (Group B), with inoperable pancreatic body cancer diagnosed during laparotomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were no intraoperative or post\u2010operative, NCPB related, complications. Patients in both groups, reported significant pain relief in the early post\u2010operative period. Using the visual analogue scale preoperatively, in second post\u2010operative day, first and third post\u2010operative month, no significant different was observed between the two groups. The mean hospital stay in both groups was 2.1 versus 5.2 (<jats:italic>P<\/jats:italic>\u2009=\u20090.0005) and the mean survival 8.1 versus 7.9\u2009months (ns).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The NCPB is feasible method for palliation in inoperable pancreatic cancer. Laparoscopic NCPB gives excellent results and could still be considered in selected cases, as an effective alternative during staging laparoscopy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.14560","type":"journal-article","created":{"date-parts":[[2018,5,15]],"date-time":"2018-05-15T23:51:01Z","timestamp":1526428261000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Laparoscopic versus open approach to neurolytic celiac plexus block in inoperable pancreatic cancer"],"prefix":"10.1111","volume":"88","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9088-4959","authenticated-orcid":false,"given":"Kostas","family":"Tepelenis","sequence":"first","affiliation":[{"name":"Department of Surgery General Hospital of Ioannina \u2018G. 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