{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T04:39:54Z","timestamp":1773808794176,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2018,6,12]],"date-time":"2018-06-12T00:00:00Z","timestamp":1528761600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Pelvic exenteration (PE) for locally advanced pelvic malignancy requires a multi\u2010disciplinary approach and is associated with significant morbidity. Urinary reconstruction forms a major component of this procedure. The aim of the study is to review the urological outcomes following PE in a newly established pelvic oncology unit, to compare with those following radical cystectomy (RC) for bladder cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients were identified from prospectively maintained PE and bladder cancer databases, inclusive of all cases performed between January 2012 and December 2016. Those without urinary reconstructions and follow\u2010up durations of less than 3 months were excluded. The outcomes of PE and RC cases were compared, stratifying surgical complications using the Clavien\u2010Dindo classification. Statistical significance was defined as <jats:italic>P<\/jats:italic> &lt; 0.05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 22 PE cases and 27 RC cases. The median age at surgery was 56 and 65 years, with a median follow\u2010up of 11.7 and 19.8 months, in the PE and RC groups, respectively. Urinary reconstructions comprised <jats:italic>n<\/jats:italic> = 20 (91%) conduit diversions and <jats:italic>n<\/jats:italic> = 2 (9%) ureteral reimplantations in the PE group, and <jats:italic>n<\/jats:italic> = 5 (19%) orthotopic bladder substitutes and <jats:italic>n<\/jats:italic> = 22 (81%) ileal conduits in the RC group. The 30\u2010day urological complication rate was 23% in the PE group (<jats:italic>n<\/jats:italic> = 4 Clavien\u2010Dindo Grade 1\u20132, and <jats:italic>n<\/jats:italic> = 1 Grade 3) versus 11% in the RC group (<jats:italic>n<\/jats:italic> = 1 Grade 1\u20132, and <jats:italic>n<\/jats:italic> = 2 Grade 3), <jats:italic>P<\/jats:italic> = 0.801. There were no Grade 4\u20135 complications in this series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The urological outcomes following PE in complex pelvic oncology are reasonable and not inferior to those after primary RC alone.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.14689","type":"journal-article","created":{"date-parts":[[2018,6,12]],"date-time":"2018-06-12T23:30:47Z","timestamp":1528846247000},"page":"896-900","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Urological outcomes following pelvic exenteration for advanced pelvic cancer are not inferior to those following radical cystectomy"],"prefix":"10.1111","volume":"88","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1512-3356","authenticated-orcid":false,"given":"Edwin J.","family":"Aslim","sequence":"first","affiliation":[{"name":"Department of Urology Singapore General Hospital  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min Hoe","family":"Chew","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Singapore General Hospital  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghee Kheng","family":"Chew","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Singapore General Hospital  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lui Shiong","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Urology Singapore General Hospital  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,6,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1503\/cjs.014010"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-009-0066-7"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2005.10.011"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2013.02.024"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2006.05.058"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2014.03.568"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2011.12.002"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.24511"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.4251\/wjgo.v9.i5.218"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-196210000-00015"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1970.tb04498.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0094-0143(05)70420-1"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.5999\/aps.2014.41.5.556"},{"issue":"5","key":"e_1_2_6_15_1","first-page":"780","article-title":"Peritoneal fluid urea nitrogen and creatinine reference values","volume":"93","author":"Manahan KJ","year":"1999","journal-title":"Obstet. 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