{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T14:52:19Z","timestamp":1778511139558,"version":"3.51.4"},"reference-count":23,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,7,30]],"date-time":"2018-07-30T00:00:00Z","timestamp":1532908800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of our study was to analyse the role of inferior mesenteric artery (IMA) ligation during elective colonic resection for diverticular disease (DD) with respect to surgical outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients who underwent elective laparoscopic or open colonic resection for DD from January 2006 to December 2012 were studied. The patients were divided into two groups based on IMA ligation or preservation. The primary end point was to compare anastomotic leakage in the two groups. The secondary end points were operative time, stoma formation, overall post\u2010operative complications, restoration of bowel function and length of post\u2010operative hospital stay.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the study period, 219 elective colonic resections with primary anastomosis for DD were performed. A laparoscopic technique was employed in 132 (60.3%) cases. IMA ligation was performed in 66 patients (30.1%). Overall anastomotic leakage rate was 4.1%, 4.5% in IMA ligation and 3.9% in IMA preservation group, respectively (<jats:italic>P<\/jats:italic>\u2009=\u2009ns). Mean operative time was 225\u2009\u00b1\u200943.4 and 191\u2009\u00b1\u200941.7 min in IMA ligation and preservation group, respectively (<jats:italic>P<\/jats:italic>\u2009=\u20090.002). No differences were observed in the rate of overall complications, stoma formation, restoration of bowel function and post\u2010operative length of hospital stay.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>No differences were observed in surgical outcome in IMA ligation and preservation groups, particularly preservation or ligation of the IMA did not affect leakage rate.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.14724","type":"journal-article","created":{"date-parts":[[2018,7,31]],"date-time":"2018-07-31T05:38:40Z","timestamp":1533015520000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Does inferior mesenteric artery ligation affect outcome in elective colonic resection for diverticular disease?"],"prefix":"10.1111","volume":"88","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9337-6765","authenticated-orcid":false,"given":"Paola","family":"De Nardi","sequence":"first","affiliation":[{"name":"Department of Gastrointestinal Surgery San Raffaele Scientific Institute  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Gazzetta","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery San Raffaele Scientific Institute  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,7,30]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2012.194"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000099480"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2007.05118.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1067\/j.cpsurg.2010.04.005"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12659"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000184843.89836.35"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2009.08.021"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12455"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2011.01.011"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(01)00681-X"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129689-200312000-00005"},{"key":"e_1_2_6_13_1","first-page":"85","article-title":"Preservation and peeling of the inferior mesenteric artery as a complication\u2010preventing technique in the anterior resection of the rectum","volume":"2","author":"Valdoni P","year":"1972","journal-title":"Surg. Italy"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000133083.54934.ae"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2012.03103.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"crossref","unstructured":"AlvesA PanisY SlimKet al.;Association Fran\u00e7ais de Chirurgie. French multicentre prospective observational study of laparoscopic versus open colectomy for sigmoid diverticular disease.Br. J. Surg.2005;92:1520\u20135.","DOI":"10.1002\/bjs.5148"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2004.03071.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2005.00867.x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.4430"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e318262a6cd"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198709000-00011"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-197305000-00002"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-6560-y"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.140.7.681"}],"container-title":["ANZ Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fans.14724","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.14724","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T22:17:57Z","timestamp":1694902677000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ans.14724"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,30]]},"references-count":23,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1111\/ans.14724"],"URL":"https:\/\/doi.org\/10.1111\/ans.14724","archive":["Portico"],"relation":{},"ISSN":["1445-1433","1445-2197"],"issn-type":[{"value":"1445-1433","type":"print"},{"value":"1445-2197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,30]]},"assertion":[{"value":"2018-02-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-05-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}