{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:39:40Z","timestamp":1747183180108,"version":"3.40.5"},"reference-count":14,"publisher":"Wiley","issue":"1-2","license":[{"start":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T00:00:00Z","timestamp":1548288000000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Currently, intraoperative use of local anaesthetic is not routinely given in all laparoscopic appendicectomies. Although its use has been widely studied in laparoscopic hernia repairs, gynaecological laparoscopy and laparoscopic cholecystectomies, there are no published trials of the use of intraperitoneal local anaesthetic during laparoscopic appendicectomy in the Australasian setting. The aim of this study was to determine whether the use of intraperitoneal ropivacaine during laparoscopic appendicectomy will reduce the amount of post\u2010operative opiate analgesia used, abdominal pain, post\u2010operative nausea or vomiting, shoulder tip pain and length of hospital stay.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A randomized double\u2010blinded placebo versus control trial was conducted with patients with clinically diagnosed appendicitis undergoing laparoscopic appendicectomy. Primary outcomes measured were the number of times the patient\u2010controlled analgesia (PCA) button was pressed post\u2010operatively and the average and total amount of fentanyl from PCA consumed during the post\u2010operative period from 0 to 6 h and from 6 to 16\u2009h.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 86 patients with 43 patients in the placebo normal saline group and 43 patients in the treatment ropivacaine group were included in the study. During the immediate post\u2010operative period (0\u20136 h), there was a statistically significant reduction in the number of times the PCA button was pressed in the ropivacaine group compared to the normal saline group (16 versus 24 times, <jats:italic>P<\/jats:italic>\u2009=\u20090.02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Intraperitoneal ropivacaine has an analgesic effect for patients up to 6 h following emergency laparoscopic appendicectomy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.15049","type":"journal-article","created":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T20:28:26Z","timestamp":1548361706000},"page":"101-105","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The role of intraperitoneal ropivacaine in laparoscopic appendicectomy: a prospective, double\u2010blinded randomized control Australian study"],"prefix":"10.1111","volume":"89","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0035-7515","authenticated-orcid":false,"given":"Yang Y.","family":"Huang","sequence":"first","affiliation":[{"name":"Department of General Surgery Armadale\u2010Kelmscott Memorial Hospital  Armadale Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arul E.","family":"Suthananthan","sequence":"additional","affiliation":[{"name":"Department of General Surgery Armadale\u2010Kelmscott Memorial Hospital  Armadale Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Hunt","sequence":"additional","affiliation":[{"name":"Department of General Surgery Armadale\u2010Kelmscott Memorial Hospital  Armadale Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Hruby","sequence":"additional","affiliation":[{"name":"Department of General Surgery Armadale\u2010Kelmscott Memorial Hospital  Armadale Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharnice","family":"Koek","sequence":"additional","affiliation":[{"name":"Department of General Surgery Armadale\u2010Kelmscott Memorial Hospital  Armadale Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alistair","family":"Rowcroft","sequence":"additional","affiliation":[{"name":"Department of General Surgery Armadale\u2010Kelmscott Memorial Hospital  Armadale Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han","family":"Beh","sequence":"additional","affiliation":[{"name":"Department of General Surgery Armadale\u2010Kelmscott Memorial Hospital  Armadale Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohan","family":"Jayasundera","sequence":"additional","affiliation":[{"name":"Department of General Surgery Armadale\u2010Kelmscott Memorial Hospital  Armadale Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,1,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-001-9181-8"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2010.05573.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.8999"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.14260\/jemds\/2015\/1484"},{"key":"e_1_2_8_6_1","unstructured":"DiZeregaGS RodgersKE. The Peritoneum.2012. p. 378. [Cited 3 Nov 2018.] Available from URL:https:\/\/books.google.com\/books?id=NASIBwAAQBAJ&pgis=1"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2017.01.022"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-018-4623-9"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2012.06210.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/147323001003800309"},{"key":"e_1_2_8_11_1","first-page":"39","article-title":"Analgesic efficacy of intraperitoneal tramadol vs. placebo for POSTOPERATIVE pain relief following laparoscopic APPENDICECTOMY: a double blinded one year randomized control trial: single centric, hospital based study","volume":"5","author":"Vivek P","year":"2016","journal-title":"J. Evol. Med. Dent. Sci."},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.14260\/jemds\/2016\/1111"},{"key":"e_1_2_8_13_1","first-page":"399","article-title":"Subcutaneous versus subcutaneous and intraperitoneal local anaesthetic in the management of post appendicectomy pain","volume":"64","author":"Qureshi KZ","year":"2014","journal-title":"Pakistan Armed Forces Med J."},{"key":"e_1_2_8_14_1","first-page":"CD009060","article-title":"Methods of intraperitoneal local anaesthetic instillation for laparoscopic cholecystectomy","volume":"3","author":"Gurusamy KS","year":"2014","journal-title":"Cochrane Database Syst. Rev."},{"key":"e_1_2_8_15_1","first-page":"CD007337","article-title":"Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for laparoscopic cholecystectomy","volume":"3","author":"Gurusamy KS","year":"2014","journal-title":"Cochrane Database Syst. Rev."}],"container-title":["ANZ Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fans.15049","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.15049","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T01:56:06Z","timestamp":1694656566000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ans.15049"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":14,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1111\/ans.15049"],"URL":"https:\/\/doi.org\/10.1111\/ans.15049","archive":["Portico"],"relation":{},"ISSN":["1445-1433","1445-2197"],"issn-type":[{"type":"print","value":"1445-1433"},{"type":"electronic","value":"1445-2197"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"2018-11-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}