{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T07:14:01Z","timestamp":1777619641781,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T00:00:00Z","timestamp":1554768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Minimally invasive pancreaticoduodenectomy (PD) is a feasible option for periampullary tumours. However, it remains a complex procedure with no proven advantages over open PD (OPD). The aim of the study was to compare the outcomes between laparoscopic\u2010assisted PD (LAPD) and OPD using a propensity score\u2010matched analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective review of 40 patients who underwent PD for periampullary tumours between January 2014 and December 2016 was conducted. The patients were matched 1:1 for age, gender, body mass index, Charlson comorbidty index, tumour size and haematological indices. Peri\u2010operative outcomes were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>LAPD appeared to have a longer median operative time as compared to OPD (LAPD, 425\u2009min (285\u2013597) versus OPD, 369\u2009min (260\u2013500)) (<jats:italic>P<\/jats:italic>\u2009=\u20090.066). Intra\u2010operative blood loss was comparable between both groups. Respiratory complications were five times higher in the OPD group (LAPD, 5% versus OPD, 25%) (<jats:italic>P<\/jats:italic>\u2009=\u20090.077), while LAPD patients required less time to start ambulating post\u2010operatively (LAPD, 2 days versus OPD, 2 days) (<jats:italic>P<\/jats:italic>\u2009=\u20090.021). Pancreas\u2010specific complications and morbidity\/mortality rates were similar.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LAPD is a safe alternative to OPD in a select group of patients for an institution starting out with minimally invasive PD, and can be used to bridge the learning curve required for total laparoscopic PD.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.15124","type":"journal-article","created":{"date-parts":[[2019,4,10]],"date-time":"2019-04-10T00:14:55Z","timestamp":1554855295000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Propensity score\u2010matched analysis of early outcomes after laparoscopic\u2010assisted versus open pancreaticoduodenectomy"],"prefix":"10.1111","volume":"89","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7798-3936","authenticated-orcid":false,"given":"Jarrod K. H.","family":"Tan","sequence":"first","affiliation":[{"name":"Division of Hepatopancreaticobiliary Surgery and Liver Transplantation, Department of Surgery National University Health System  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun Jie","family":"Ng","sequence":"additional","affiliation":[{"name":"Division of Hepatopancreaticobiliary Surgery and Liver Transplantation, Department of Surgery National University Health System  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Yeo","sequence":"additional","affiliation":[{"name":"Yong Loo Lin School of Medicine National University of Singapore  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederick H. X.","family":"Koh","sequence":"additional","affiliation":[{"name":"Division of Hepatopancreaticobiliary Surgery and Liver Transplantation, Department of Surgery National University Health System  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glenn K.","family":"Bonney","sequence":"additional","affiliation":[{"name":"Division of Hepatopancreaticobiliary Surgery and Liver Transplantation, Department of Surgery National University Health System  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iyer S.","family":"Ganpathi","sequence":"additional","affiliation":[{"name":"Division of Hepatopancreaticobiliary Surgery and Liver Transplantation, Department of Surgery National University Health System  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishnakumar","family":"Madhavan","sequence":"additional","affiliation":[{"name":"Division of Hepatopancreaticobiliary Surgery and Liver Transplantation, Department of Surgery National University Health System  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8942-8262","authenticated-orcid":false,"given":"Alfred W. 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