{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T22:43:39Z","timestamp":1768257819614,"version":"3.49.0"},"reference-count":20,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,7,31]],"date-time":"2019-07-31T00:00:00Z","timestamp":1564531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>This study investigates the incidence of post\u2010operative complications and risk factors of sentinel lymph node biopsy (SLNB) in melanoma patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort study was conducted at a single cancer institution on 408 consecutive SLNBs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010five post\u2010operative complications occurred in 39 (9.5%) patients and included: wound infection in 24 (5.9%), seroma and lymphorrhea in 15 (3.7%), wound dehiscence in seven (1.7%), lymphocele in six (1.5%) and others in three (0.7%). Univariate analysis failed to identify possible risk factors (i.e. gender, age, lymph node region, number of excised lymph nodes, Breslow index, pT levels, comorbidities, length of surgery and hospital stay). Metastatic sentinel nodes occurred in four of 135 (3%) patients with thin melanoma (Breslow &lt;1 mm) and in 68 of 262 (25.9%) patients with Breslow &gt;1 mm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>For patients with thin melanoma in whom the incidence of lymph node metastasis is low, the reported post\u2010operative morbidity of almost 10% of SLNB highlights the need for careful patient selection.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.15358","type":"journal-article","created":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:38:28Z","timestamp":1564619908000},"page":"1041-1044","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Sentinel lymph node biopsy in patients with malignant melanoma: analysis of post\u2010operative complications"],"prefix":"10.1111","volume":"89","author":[{"given":"Nicola","family":"Solari","sequence":"first","affiliation":[{"name":"Department of Surgery Surgery Unit 1, San Martino Hospital  Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7235-3444","authenticated-orcid":false,"given":"Sergio","family":"Bertoglio","sequence":"additional","affiliation":[{"name":"Department of Surgery Surgery Unit 1, San Martino Hospital  Genoa Italy"},{"name":"Department of Surgical Sciences University of Genoa  Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandru","family":"Boscaneanu","sequence":"additional","affiliation":[{"name":"Department of Surgery Surgery Unit 1, San Martino Hospital  Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Minuto","sequence":"additional","affiliation":[{"name":"Department of Surgery Surgery Unit 1, San Martino Hospital  Genoa Italy"},{"name":"Department of Surgical Sciences University of Genoa  Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simona","family":"Reina","sequence":"additional","affiliation":[{"name":"Department of Surgery Surgery Unit 1, San Martino Hospital  Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denise","family":"Palombo","sequence":"additional","affiliation":[{"name":"Department of Surgery Surgery Unit 1, San Martino Hospital  Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Bruzzi","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology San Martino Hospital  Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferdinando","family":"Cafiero","sequence":"additional","affiliation":[{"name":"Department of Surgery Surgery Unit 1, San Martino Hospital  Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,7,31]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"AIOM Working Group; AIRTUM Working Group.I numeri del cancro in Italia.2016. 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