{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T14:37:06Z","timestamp":1777473426402,"version":"3.51.4"},"reference-count":30,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,8,23]],"date-time":"2019-08-23T00:00:00Z","timestamp":1566518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The optimal methods for patients with difficult biliary stones remain under debate. The aim of this study was to evaluate the role of frequency\u2010doubled double\u2010pulse neodymium YAG (FREDDY) laser lithotripsy for removing difficult biliary stones during laparoscopic common bile duct exploration (LCBDE).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between March 2013 and January 2015, 42 consecutive patients with difficult biliary stones who underwent LCBDE with FREDDY laser lithotripsy were included in this study. The clinical data of all patients were retrospectively collected and analysed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Bile ducts were completely cleared in all patients. The complications related to laser lithotripsy were not noted. A total of 38 patients (90.5%) underwent primary closure of common bile duct, and T\u2010tube drainage was applied to four patients (9.5%). No bile duct injury, bleeding and perforation were observed. There were no post\u2010operative surgery\u2010related deaths. Bile leakage occurred in four patients (9.5%) with primary closure procedure, and all of them were managed successfully with conservative therapy. The median follow\u2010up period was 42.8 months, with no evidence of bile duct stricture and stone recurrence in all patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The LCBDE combined with FREDDY laser lithotripsy appear to be effective and safe for the treatment of difficult biliary stones.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.15364","type":"journal-article","created":{"date-parts":[[2019,8,23]],"date-time":"2019-08-23T08:29:07Z","timestamp":1566548947000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Clinical role of frequency\u2010doubled double\u2010pulse neodymium YAG laser lithotripsy for removal of difficult biliary stones in laparoscopic common bile duct exploration"],"prefix":"10.1111","volume":"89","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3374-1142","authenticated-orcid":false,"given":"Tingsong","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Hepatobiliary and Pancreatic Surgery, Cholelithiasis Treatment Center Shanghai Tenth People's Hospital, Tongji University of Medicine  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhilong","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary and Pancreatic Surgery, Cholelithiasis Treatment Center Shanghai Tenth People's Hospital, Tongji University of Medicine  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary and Pancreatic Surgery, Cholelithiasis Treatment Center Shanghai Tenth People's Hospital, Tongji University of Medicine  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary and Pancreatic Surgery, Cholelithiasis Treatment Center Shanghai Tenth People's Hospital, Tongji University of Medicine  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongbo","family":"Meng","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary and Pancreatic Surgery, Cholelithiasis Treatment Center Shanghai Tenth People's Hospital, Tongji University of Medicine  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dalu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary and Pancreatic Surgery, Cholelithiasis Treatment Center Shanghai Tenth People's Hospital, Tongji University of Medicine  Shanghai China"},{"name":"Department of General Surgery, Shanghai Clinical Medical College of Anhui Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary and Pancreatic Surgery, Cholelithiasis Treatment Center Shanghai Tenth People's Hospital, Tongji University of Medicine  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenshun","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary and Pancreatic Surgery, Cholelithiasis Treatment Center Shanghai Tenth People's Hospital, Tongji University of Medicine  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,8,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(02)70005-9"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v12.i20.3162"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-015-4523-0"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-013-3015-3"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(00)00368-8"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-016-5388-6"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000368326"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2014.06.013"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinre.2015.02.002"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2016.0004"},{"key":"e_1_2_6_12_1","first-page":"AB87","article-title":"First clinical data on laser lithotripsy of common bile duct stones with a new frequency\u2010doubled double\u2010pulse ND:YAG\u2010laser (FREDDY) in 19 patients","volume":"53","author":"Hochberger J","year":"2001","journal-title":"Gastrointest. 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