{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T05:43:00Z","timestamp":1778996580164,"version":"3.51.4"},"reference-count":31,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,5,25]],"date-time":"2020-05-25T00:00:00Z","timestamp":1590364800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2019SCUH"],"award-info":[{"award-number":["2019SCUH"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To outline our experience with the radical resection of hilar cholangiocarcinoma (HCCA) combined with the partial resection of the pancreatic head (RRHCCAPRPH) as a treatment for HCCA with distal bile duct involvement and to appraise the feasibility of this challenging procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between 2007 and 2017, 205 patients with HCCA who underwent curative surgery at our hospital were included. Among the patients, extrahepatic bile duct resection combined with hepatectomy (EBDRH), RRHCCAPRPH and hepatopancreaticoduodenectomy (HPD) was performed in 168, 21 and 16 patients, respectively. Clinical pathological factors, post\u2010operative complications and survival were compared between the three groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was a significant difference in operative blood loss, operative time, post\u2010operative hospital stay and tumour size between EBDRH group, RRHCCAPRPH group and HPD group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). In terms of post\u2010operative complications, there was no statistical difference between the three groups (<jats:italic>P<\/jats:italic> = 0.177). Further analysis showed that the incidence of pancreatic fistula (43.8%) and delayed gastric emptying (25%) after HPD were significantly higher than the other two groups. The median survival time and overall survival rate for 172 patients with R0 resection were 33\u2009months and 85.5% at 1 year, 47.7% at 3\u2009years, 28.4% at 5\u2009years. Furthermore, the 1\u2010, 3\u2010 and 5\u2010year survival rates of patients with EBDRH, RRHCCAPRPH and HPD after R0 resection were 86.2%, 48.7%, 29.2%; 85.0%, 44.0%, 24.7% and 78.6%, 42.9%, 22.9%, respectively (<jats:italic>P<\/jats:italic> = 0.948).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The RRHCCAPRPH in some selected patients can actually replace HPD as a surgical treatment for HCCA with distal bile duct involvement.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.15955","type":"journal-article","created":{"date-parts":[[2020,5,26]],"date-time":"2020-05-26T04:01:35Z","timestamp":1590465695000},"page":"1666-1670","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Is radical resection of hilar cholangiocarcinoma plus partial resection of pancreatic head justified for advanced hilar cholangiocarcinoma?"],"prefix":"10.1111","volume":"90","author":[{"given":"Fei","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Biliary Surgery West China Hospital of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hai\u2010Jie","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Biliary Surgery West China Hospital of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen\u2010Jie","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Biliary Surgery West China Hospital of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun\u2010Ke","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Biliary Surgery West China Hospital of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cong\u2010Dun","family":"Ran","sequence":"additional","affiliation":[{"name":"Department of Biliary Surgery West China Hospital of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parbatraj","family":"Regmi","sequence":"additional","affiliation":[{"name":"Department of Biliary Surgery West China Hospital of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8605-3087","authenticated-orcid":false,"given":"Fu\u2010Yu","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Biliary Surgery West China Hospital of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,5,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-007-0453-z"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3182368f85"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-014-2063-z"},{"key":"e_1_2_7_5_1","first-page":"923","article-title":"Our experience (5 cases) of extended right lobectomy combined with pancreatoduodenectomy for the carcinoma of the gallbladder","volume":"7","author":"Takasaki K","year":"1980","journal-title":"Tan To Sui"},{"key":"e_1_2_7_6_1","first-page":"170","article-title":"Hepatopancreatoduodenectomy for advanced carcinoma of the biliary tract","volume":"38","author":"Nimura Y","year":"1991","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_7_7_1","first-page":"14839","article-title":"Hepato\u2010pancreatodudenectomy for hilar cholangiocarcinoma: a case report and literature review","volume":"9","author":"Yang Q","year":"2016","journal-title":"Int. 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