{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T23:34:29Z","timestamp":1767828869940,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,5,14]],"date-time":"2020-05-14T00:00:00Z","timestamp":1589414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81770566"],"award-info":[{"award-number":["81770566"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Research about the long\u2010term outcomes of oesophagogastric devascularization and splenectomy (OGDS) to treat portal hypertension (PH) is scarce. This study aimed to evaluate the safety and long\u2010term treatment efficacy of OGDS, especially in elderly patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>During 2010\u20132016, open splenectomy and oesophagogastric devascularization (OSOD) and laparoscopic splenectomy and oesophagogastric devascularization were performed in 124 (group A) and 29 (group C) patients diagnosed with PH and liver cirrhosis, respectively. All patients aged less than 65\u2009years. Besides, 39 patients aged 65\u2009years or older undergoing open splenectomy and oesophagogastric devascularization were classified into group B. All clinical data were retrospectively analysed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared with group A, patients in group C had longer operative time, less blood loss and shorter post\u2010operative hospitalization time. However, for perioperative data, there was no significant difference between group A and group B. During post\u2010operative follow\u2010up, compared with pre\u2010operative condition, all haematology and liver function parameters significantly changed, except for alanine aminotransferase. For post\u2010operative complications, only the portal vein system thrombosis rate was significantly higher in group C than group A. No significant difference was found in the overall survival rate among three groups, when non\u2010variceal\u2010rebleeding\u2010related deaths were excluded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>OGDS remains safe and effective to treat PH secondary to liver cirrhosis and it can be performed successfully in elderly patients and achieve a curative effect that is not inferior to young patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.15994","type":"journal-article","created":{"date-parts":[[2020,5,14]],"date-time":"2020-05-14T14:23:34Z","timestamp":1589466214000},"page":"2269-2273","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Long\u2010term outcomes of oesophagogastric devascularization and splenectomy in patients with portal hypertension and liver cirrhosis"],"prefix":"10.1111","volume":"90","author":[{"given":"Lingpeng","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Liver Surgery, Liver Transplantation Center West China Hospital of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zifei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Liver Surgery, Liver Transplantation Center West China Hospital of Sichuan University  Chengdu China"},{"name":"Department of General Surgery The Affiliated Hospital of Xizang Minzu University  Xianyang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinli","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Liver Surgery, Liver Transplantation Center West China Hospital of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junjie","family":"Kong","sequence":"additional","affiliation":[{"name":"Department of Liver Surgery, Liver Transplantation Center West China Hospital of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8696-4844","authenticated-orcid":false,"given":"Xianwei","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Liver Surgery, Liver Transplantation Center West China Hospital of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7930-4186","authenticated-orcid":false,"given":"Wentao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Liver Surgery, Liver Transplantation Center West China Hospital of Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,5,14]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2008.01.021"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gassur.2004.09.028"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2006.08.023"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0901512"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2000.00778.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)06283-1"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2002.30418"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/003655202317284138"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-003-0367-5"},{"key":"e_1_2_8_11_1","first-page":"648","article-title":"Nonshunt operations in portal hypertension without cirrhosis","volume":"131","author":"Hassab MA","year":"1970","journal-title":"Surg. 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