{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:39:15Z","timestamp":1747183155121,"version":"3.40.5"},"reference-count":16,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,6,21]],"date-time":"2020-06-21T00:00:00Z","timestamp":1592697600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Quite a few studies on anal functions after open total mesorectal excision combined with transanal intersphincteric resection (ISR) have been reported, but there is little literature on anal function after laparoscopic total mesorectal excision (LTME) combined with transanal ISR. The aim of this study was to explore the post\u2010operative anorectal dynamic changes in ultra\u2010low rectal cancer patients undergoing LTME combined with transanal ISR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The data of 26 ultra\u2010low rectal cancer patients undergoing LTME\u2009+\u2009transanal ISR were analysed. A total of 30 patients undergoing laparoscopic low anterior resection by the same surgeons during the same period were randomly enrolled into the control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were no differences in the preoperative anorectal manometry data and Wexner anal function scores between the observation group and the control group (<jats:italic>P<\/jats:italic> &gt;\u20090.05). There were no significant differences in the mean operation time, the mean amount of bleeding and the mean post\u2010operative hospital stay between the two groups (<jats:italic>P<\/jats:italic> &gt;\u20090.05). The mean follow\u2010up time was 16\u2009months. No recurrence and metastasis were found in all cases. At 3 and 6 months after the operation, there were significant differences in the anorectal manometry data and Wexner anal function scores between the two groups (<jats:italic>P<\/jats:italic> &lt;\u20090.05). However, at 1 year after the operation, there were no significant differences in the anorectal manometry data and Wexner anal function scores between the two groups (<jats:italic>P<\/jats:italic> &gt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Laparoscopic ISR for ultra\u2010low rectal cancer is technically feasible, but the surgical indications should be strictly defined.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.16077","type":"journal-article","created":{"date-parts":[[2020,6,21]],"date-time":"2020-06-21T22:14:26Z","timestamp":1592777666000},"page":"2478-2483","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Study of anorectal dynamics in patients undergoing laparoscopic ultra\u2010low resection and transanal intersphincteric resection for rectal cancer"],"prefix":"10.1111","volume":"90","author":[{"given":"Si","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Gastrointestinal Surgery The First People's Hospital of Foshan (Foshan Hospital of Sun Yat\u2010sen University)  Foshan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4593-5689","authenticated-orcid":false,"given":"Jianzhong","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery The First People's Hospital of Foshan (Foshan Hospital of Sun Yat\u2010sen University)  Foshan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tedong","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery The First People's Hospital of Foshan (Foshan Hospital of Sun Yat\u2010sen University)  Foshan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zuojun","family":"Zhen","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery The First People's Hospital of Foshan (Foshan Hospital of Sun Yat\u2010sen University)  Foshan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1490-6327","authenticated-orcid":false,"given":"Yong","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery The First People's Hospital of Foshan (Foshan Hospital of Sun Yat\u2010sen University)  Foshan China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,6,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(92)90042-P"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02237232"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-010-1451-x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-009-1150-x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-006-0243-8"},{"key":"e_1_2_7_7_1","first-page":"203","article-title":"Laparoscopic pelvic approach to ISR for ULAR","volume":"30","author":"Chi P","year":"2010","journal-title":"Chinese Journal of Practical Surgery(Chinese)"},{"key":"e_1_2_7_8_1","first-page":"79","article-title":"LTME combined with transanal intersphincteric resection for the treatment of ultra\u2010low rectal cancer","volume":"15","author":"Deng J","year":"2012","journal-title":"Chinese Journal of Gastrointestinal Surgery(Chinese)"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02238569"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02062019"},{"key":"e_1_2_7_11_1","first-page":"8493","article-title":"Effect of different body position on anorectal manometry for chronic constipation patients","volume":"23","author":"Su H","year":"2019","journal-title":"Eur. 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