{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:39:35Z","timestamp":1747183175966,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,8,24]],"date-time":"2020-08-24T00:00:00Z","timestamp":1598227200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The aim was to study the outcomes of acute pancreatitis (AP) patients who were referred from other facilities to a tertiary care centre.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with AP were who were referred from other hospitals to a tertiary care centre between April 2013 and September 2019 were studied and their outcomes were analysed. Comparison was made between patients referred early (\u22647\u2009days) versus those referred late (&gt;7\u2009days).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 838 patients seen by us, 650 patients (77.6%) were referred from other centres. Median (interquartile range) onset to admission interval was 5 (4\u20137) days for those who were referred \u22647\u2009days and was 16 (11\u201330) for those who were referred &gt;7\u2009days. Patients referred beyond 7\u2009days of pain onset had higher rates of development of organ failure (<jats:italic>P<\/jats:italic> = 0.007), including acute lung injury (<jats:italic>P<\/jats:italic> = 0.008) and acute kidney injury (<jats:italic>P<\/jats:italic> = 0.026), infected necrosis (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001), requirement of endoscopic\/percutaneous drainage (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and need for surgery (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.02) compared to patients who were referred \u22647\u2009days of pain onset. Mortality was however similar in the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients with AP referred to a specialized centre with AP early (\u22647\u2009days) have better outcomes than those referred late (&gt;7\u2009days) from other facilities.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.16238","type":"journal-article","created":{"date-parts":[[2020,8,25]],"date-time":"2020-08-25T07:43:20Z","timestamp":1598341400000},"page":"2015-2019","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Delayed referral increases the need for surgery and intervention in patients with acute pancreatitis"],"prefix":"10.1111","volume":"90","author":[{"given":"Gaurav","family":"Muktesh","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Postgraduate Institute of Medical Education and Research  Chandigarh 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