{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:33:23Z","timestamp":1787319203313,"version":"build-2736575974"},"reference-count":20,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,12,28]],"date-time":"2020-12-28T00:00:00Z","timestamp":1609113600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Splenic abscess has been an uncommon entity which is now being encountered more frequently due to increased prevalence of immunodeficiency disorders and chronic illnesses. This study was aimed to audit our experience with splenic abscesses at a tertiary care centre in India highlighting usefulness of an algorithmic approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective analysis of data of patients (January 2014 to December 2019) with splenic abscess was done. Data were retrieved for clinical characteristics, radiological findings, organism spectra, abscess characteristics, therapeutic measures and clinical outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The mean age of the study population (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a036) was 41.3\u2009\u00b1\u200919.0\u2009years with 50% males. Comorbidities were identified in 17 (47.2%) patients, with diabetes mellitus being the commonest. Fever and abdominal pain were the most common presenting features. Multiple splenic abscesses were present in 21 (58.3%) patients. Extra\u2010splenic abscesses in liver were seen in five (13.9%) patients while nine (25%) patients had ruptured splenic abscess. Microorganisms were identified in 24 (66.7%) patients, with\n                      <jats:italic>Salmonella typhi<\/jats:italic>\n                      being the commonest (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a09, 25%) followed by\n                      <jats:italic>Escherichia coli<\/jats:italic>\n                      (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a07, 19.4%) and\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                      (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a04, 11.1%). Six patients received only antimicrobials, 24 were managed with percutaneous aspiration or catheter drainage and six required surgery. Five (13.9%) patients died, with highest mortality being seen in those who received only antimicrobial (50%), compared to percutaneous aspiration or catheter drainage (8.3%) and surgery (0%),\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.017.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Using percutaneous aspiration or drainage in conjunction with antibiotics, followed by surgery in non\u2010responder, patients with splenic abscesses can be managed successfully with acceptable mortality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ans.16517","type":"journal-article","created":{"date-parts":[[2020,12,28]],"date-time":"2020-12-28T15:38:39Z","timestamp":1609169919000},"page":"1819-1825","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Splenic abscess in a tertiary care centre in India: clinical characteristics and prognostic factors"],"prefix":"10.1111","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7610-1807","authenticated-orcid":false,"given":"Anupam K.","family":"Singh","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saurabh","family":"Karmani","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Maharishi Markandeshwar Institute of Medical Sciences and Research  Mullana India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayanta","family":"Samanta","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3914-3757","authenticated-orcid":false,"given":"Pankaj","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Radiology Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4105-3307","authenticated-orcid":false,"given":"Vikas","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3546-8610","authenticated-orcid":false,"given":"Thakur D.","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Savita","family":"Kumari","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Usha","family":"Dutta","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saroj K.","family":"Sinha","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rakesh","family":"Kochhar","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(76)90331-4"},{"key":"e_1_2_8_3_1","first-page":"686","article-title":"Splenic abscess","volume":"79","author":"Lawhorne TW","year":"1976","journal-title":"Surgery"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365549009027098"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(73)90010-X"},{"key":"e_1_2_8_6_1","first-page":"11","article-title":"Computed tomography of the spleen","volume":"35","author":"Srp A","year":"1989","journal-title":"Acta Univ. 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