{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T13:52:17Z","timestamp":1764510737349,"version":"3.40.5"},"reference-count":23,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T00:00:00Z","timestamp":1619481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Breast magnetic resonance imaging (MRI) use for surgical staging is increasing, though remains controversial. We aimed to evaluate the accuracy of MRI in surgical decision\u2010making to determine if mastectomy prompted by MRI was appropriate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A single\u2010centre observational study in Perth, Western Australia, with the inclusion of all preoperative and postoperative studies (e.g. involved margins after breast\u2010conserving surgery) undergoing staging breast MRI from 1 January 2015 to 26 August 2019. A standard protocol using gadolinium contrast was used. The reference standard was postoperative histopathology or, for studies without additional surgery after MRI following breast\u2010conserving surgery, the next and subsequent annual screening episodes. By reviewing the final histopathology, the medical case notes and multidisciplinary team decision process, we evaluated whether the reported MRI disease extent was accurate in prompting an appropriate upgrade to mastectomy. Outcomes are reported with descriptive statistics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 130 cancers staged with MRI; seven were excluded as information was incomplete, 104 were performed preoperatively and 19 postoperatively. The majority (60%) staged lobular carcinoma (invasive 59%, <jats:italic>in situ<\/jats:italic> 1%) compared to ductal carcinoma (invasive 31%, <jats:italic>in situ<\/jats:italic> 8%). For preoperative MRI, half (54% \u2013 56\/104) underwent subsequent mastectomy. Of these, MRI prompted mastectomy in 45% (25\/56), all appropriate for disease extent. In the postoperative staging group, two mastectomies were performed, one planned before imaging, the other prompted when MRI diagnosed residual disease and confirmed on histopathology. No false\u2010negative staging MRI was identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In our cohort, MRI prompted an upgrade to mastectomy in 21% (26\/123), appropriate for cancer extent.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.16887","type":"journal-article","created":{"date-parts":[[2021,4,28]],"date-time":"2021-04-28T04:40:40Z","timestamp":1619584840000},"page":"1772-1778","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Is staging breast magnetic resonance imaging prompted upgrade to mastectomy appropriate?"],"prefix":"10.1111","volume":"91","author":[{"given":"Thilina","family":"Jayaratne","sequence":"first","affiliation":[{"name":"Department of Radiology Sir Charles Gairdner Hospital  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0035-7515","authenticated-orcid":false,"given":"Yang Yang","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Surgery Sir Charles Gairdner Hospital  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Jacques","sequence":"additional","affiliation":[{"name":"Department of Research Sir Charles Gairdner Hospital  Perth Western Australia Australia"},{"name":"Institute for Health Research The University of Notre Dame  Fremantle Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravinder","family":"Dhillon","sequence":"additional","affiliation":[{"name":"Department of Radiology Sir Charles Gairdner Hospital  Perth Western Australia Australia"},{"name":"BreastScreenWA  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gareth","family":"Porter","sequence":"additional","affiliation":[{"name":"Department of Radiology Sir Charles Gairdner Hospital  Perth Western Australia Australia"},{"name":"BreastScreenWA  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharmistha","family":"Bose","sequence":"additional","affiliation":[{"name":"Department of Radiology Sir Charles Gairdner Hospital  Perth Western Australia Australia"},{"name":"BreastScreenWA  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anita","family":"Bourke","sequence":"additional","affiliation":[{"name":"Department of Radiology Sir Charles Gairdner Hospital  Perth Western Australia Australia"},{"name":"BreastScreenWA  Perth Western Australia Australia"},{"name":"Faculty of Health and Medical Sciences The University of Western Australia  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ben","family":"Dessauvagie","sequence":"additional","affiliation":[{"name":"Faculty of Health and Medical Sciences The University of Western Australia  Perth Western Australia Australia"},{"name":"Anatomical Pathology PathWest Laboratory Medicine WA  Perth Western Australia Australia"},{"name":"Anatomical Pathology Fiona Stanley Hospital  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6906-588X","authenticated-orcid":false,"given":"Glen","family":"Lo","sequence":"additional","affiliation":[{"name":"Department of Radiology Sir Charles Gairdner Hospital  Perth Western Australia Australia"},{"name":"BreastScreenWA  Perth Western Australia Australia"},{"name":"Faculty of Health and Medical Sciences The University of Western Australia  Perth Western Australia Australia"},{"name":"Medical School Curtin University  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,4,27]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_9_2_1","DOI":"10.1016\/s0140-6736(09)62070-5"},{"doi-asserted-by":"publisher","key":"e_1_2_9_3_1","DOI":"10.1200\/JCO.2007.15.2108"},{"doi-asserted-by":"publisher","key":"e_1_2_9_4_1","DOI":"10.1016\/j.mric.2010.02.005"},{"doi-asserted-by":"publisher","key":"e_1_2_9_5_1","DOI":"10.1016\/j.crad.2013.07.016"},{"doi-asserted-by":"publisher","key":"e_1_2_9_6_1","DOI":"10.1111\/1754-9485.13009"},{"doi-asserted-by":"publisher","key":"e_1_2_9_7_1","DOI":"10.1056\/nejmoa065447"},{"doi-asserted-by":"publisher","key":"e_1_2_9_8_1","DOI":"10.1148\/radiol.12120629"},{"doi-asserted-by":"publisher","key":"e_1_2_9_9_1","DOI":"10.1200\/jco.2008.21.5756"},{"doi-asserted-by":"publisher","key":"e_1_2_9_10_1","DOI":"10.1186\/bcr767"},{"doi-asserted-by":"publisher","key":"e_1_2_9_11_1","DOI":"10.1097\/sla.0b013e31827a8d17"},{"doi-asserted-by":"publisher","key":"e_1_2_9_12_1","DOI":"10.1007\/s10549-009-0616-6"},{"unstructured":"Health AGD of. 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Medicare Benefits Schedule New MBS Items for Magnetic Resonance Imaging for Breast Cancer \u2013 Factsheet Page 1 of 2 MBS Online New Medicare Benefits Schedule (MBS) Items for Magnetic Resonance Imaging (MRI) for Breast Cancer Factsheet n.d.2019http:\/\/www.mbsonline.gov.au\/internet\/mbsonline\/publishing.nsf\/Content\/Factsheet-MRIBreastCa.","key":"e_1_2_9_13_1"},{"doi-asserted-by":"publisher","key":"e_1_2_9_14_1","DOI":"10.1016\/j.jamcollsurg.2009.04.010"},{"doi-asserted-by":"publisher","key":"e_1_2_9_15_1","DOI":"10.1001\/jamaoncol.2015.3018"},{"doi-asserted-by":"publisher","key":"e_1_2_9_16_1","DOI":"10.5694\/mja16.00002"},{"doi-asserted-by":"publisher","key":"e_1_2_9_17_1","DOI":"10.1259\/bjr.20150679"},{"doi-asserted-by":"publisher","key":"e_1_2_9_18_1","DOI":"10.1016\/j.ejso.2010.12.011"},{"doi-asserted-by":"publisher","key":"e_1_2_9_19_1","DOI":"10.1148\/rg.341135034"},{"doi-asserted-by":"publisher","key":"e_1_2_9_20_1","DOI":"10.1111\/1754-9485.12296"},{"doi-asserted-by":"publisher","key":"e_1_2_9_21_1","DOI":"10.1016\/j.ejrad.2020.109130"},{"doi-asserted-by":"publisher","key":"e_1_2_9_22_1","DOI":"10.1002\/jso.21406"},{"doi-asserted-by":"publisher","key":"e_1_2_9_23_1","DOI":"10.1200\/jco.2013.52.7515"},{"doi-asserted-by":"publisher","key":"e_1_2_9_24_1","DOI":"10.2214\/ajr.13.11355"}],"container-title":["ANZ Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.16887","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ans.16887","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.16887","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T09:18:47Z","timestamp":1692868727000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ans.16887"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,27]]},"references-count":23,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["10.1111\/ans.16887"],"URL":"https:\/\/doi.org\/10.1111\/ans.16887","archive":["Portico"],"relation":{},"ISSN":["1445-1433","1445-2197"],"issn-type":[{"type":"print","value":"1445-1433"},{"type":"electronic","value":"1445-2197"}],"subject":[],"published":{"date-parts":[[2021,4,27]]},"assertion":[{"value":"2020-09-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}