{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T08:56:00Z","timestamp":1765356960962,"version":"3.40.5"},"reference-count":32,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2021,6,21]],"date-time":"2021-06-21T00:00:00Z","timestamp":1624233600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Meckel's diverticulum (MD) is the most common congenital malformation in the gastrointestinal tract. Limited up\u2010to\u2010date evidence is available regarding MD in pregnancy. We aim to review the available pertinent literature to help support clinical decision making and patient management in the future.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>The search term \u2018Meckel's diverticulum\u2018 was combined with \u2018pregnant\u2019 or \u2018pregnancy\u2019. Database searches of EMBASE, Medline and PubMed were conducted. All papers published in English from 01\/01\/1990 to 01\/01\/2021 were included. Simple statistical analysis (<jats:italic>t<\/jats:italic>\u2010test) was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010seven cases were included. Average age\u00a0=\u00a026.9\u2009years. Average gestation\u00a0=\u00a025.1\u2009weeks. Occurrence: first trimester\u00a0=\u00a03.7%; second trimester\u00a0=\u00a048.1% and third trimester\u00a0=\u00a048.1%. Presenting symptoms: abdominal pain 88.9%; nausea\/vomiting 59.3%; fever 18.5%; abdominal distension 18.5%; haematochezia 11.1%; constipation 11.1%; haematemesis 3.7%, diarrhoea 3.7% and asymptomatic 3.7%. Mean duration of preceding symptoms\u00a0=\u00a03.4\u2009days. Diagnostic imaging modalities utilised: ultrasound\u00a0=\u00a040.7%; CT\u00a0=\u00a025.9%; MRI\u00a0=\u00a014.8%; abdominal X\u2010ray\u00a0=\u00a011.1% and endoscopy\u00a0=\u00a07.4%. All cases required definite surgical management: laparotomy\u00a0=\u00a065.4%; laparoscopy\u00a0=\u00a015.4%; C\u2010section\u00a0=\u00a019.2% and unreported\u00a0=\u00a03.8%. Main intra\u2010operative findings: perforated MD\u00a0=\u00a040.7%; intussusception with MD as a lead point\u00a0=\u00a011.1%; bleeding MD\u00a0=\u00a011.1%, inflamed MD\u00a0=\u00a011.1%; small bowel obstruction\u00a0=\u00a011.1%; gangrenous MD\u00a0=\u00a03.7%; volvulus\u00a0=\u00a03.7% and unspecified\u00a0=\u00a07.4%. Mean length from ileocolic junction\u00a0=\u00a051.7\u00a0cm. Average length of stay was 7.1\u2009days. <jats:italic>T<\/jats:italic>\u2010test (<jats:italic>p<\/jats:italic>\u2010value\u00a0=\u00a00.12) when comparing management strategy. Three maternal complications and two foetal mortalities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>MD and associated pathology are difficult to diagnose in the pregnant cohort. Current imaging demonstrates low diagnostic accuracy and a deviation away from recognised nuclear medicine investigations. Surgery appears the definitive management with both open and laparoscopic approaches utilised. Significant maternal morbidity and foetal mortality are associated with this condition.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.17014","type":"journal-article","created":{"date-parts":[[2021,6,21]],"date-time":"2021-06-21T13:30:25Z","timestamp":1624282225000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Systematic review of Meckel's diverticulum in pregnancy"],"prefix":"10.1111","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8012-4497","authenticated-orcid":false,"given":"Joshua You Jing","family":"Wong","sequence":"first","affiliation":[{"name":"West Hertfordshire Hospitals NHS Trust  Vicarage Rd, Watford, Hertfordshire WD18 0HB UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Conroy","sequence":"additional","affiliation":[{"name":"Western Sussex Hospitals NHS Trust  Chichester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Farkas","sequence":"additional","affiliation":[{"name":"Western Sussex Hospitals NHS Trust  Chichester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,6,21]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/014107680609901011"},{"key":"e_1_2_9_3_1","first-page":"421","article-title":"Uber die Diveetikel am Darmkanal","volume":"9","author":"Meckel JF","year":"1809","journal-title":"Arch physiol"},{"key":"e_1_2_9_4_1","first-page":"353","article-title":"Complications of Meckel's diverticula in adults","volume":"49","author":"Dumper J","year":"2006","journal-title":"Can J Surg"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(78)90238-6"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJWH.S151501"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/1319-3767.58760"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviscsurg.2017.06.006"},{"issue":"3","key":"e_1_2_9_9_1","first-page":"1167","article-title":"Meckel's diverticulum in children, clinical and pathological aspects","volume":"55","author":"St\u0103nescu GL","year":"2014","journal-title":"Rom J Morphol Embryol"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181ef488d"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/rjw225"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2000.105396"},{"volume-title":"Appendicitis","year":"2021","author":"Jones MW","key":"e_1_2_9_13_1"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/ans.14503"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2010.29.10.1457"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.4074"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.166.3.8623629"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.14.13898"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2018180318"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.10.6351"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13017-019-0254-1"},{"key":"e_1_2_9_22_1","unstructured":"Titley\u2010DiazWH AzizM.Meckel Scan StatPearls [Internet]:StatPearls Publishing;2020[Available from:https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK560500\/."},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2017.09.008"},{"key":"e_1_2_9_24_1","first-page":"732","article-title":"Detection of ectopic gastric mucosa in Meckel's diverticulum and in other aberrations by scintigraphy: ii. 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