{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T07:49:28Z","timestamp":1790754568610,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"7-8","license":[{"start":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T00:00:00Z","timestamp":1625443200000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>While socioeconomic deprivation has been shown to affect survival in colorectal cancer, other factors such as global region of birth and ethnicity also exert an effect. We wished to ascertain the influence of socioeconomic deprivation on stage of presentation and cancer survival in an ethnically diverse Australian population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Cases from a database of resections in Western Sydney (<jats:italic>n<\/jats:italic>\u00a0=\u00a01596) were stratified into cohorts of socioeconomic quintiles. Univariate analysis was used to compare demographics, AJCC stage and histopathological details between the least and most socioeconomically deprived groups. Kaplan\u2013Meier analysis and log\u2010rank testing were used to compare cancer\u2010specific and all\u2010cause 5\u2010year survival between the most deprived quintile and all others, after case\u2013control matching for age and overseas birth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 322 (20.2%) patients from the most socioeconomically deprived centile, and 275 (17.2%) from the least were compared. The most deprived were significantly more likely to be aged under 70 (54.1% vs. 44.4%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.019), born overseas (54.3% vs. 38.6%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.003), present with stage III disease (37.4% vs. 26.7%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.005), perforated (12.5% vs. 5.3%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.005) or circumferential tumours (37% vs. 24.3%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.043). There was no significant difference in proportions presenting with metastatic disease, or 5\u2010year survival between the most deprived quintile and all others after correction for age and foreign birth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Socioeconomic deprivation is associated with unfavourable colorectal cancer presentation stage but not poorer 5\u2010year survival in our Western Sydney population. The reasons for this are unclear and demand further attention.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.17048","type":"journal-article","created":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T13:57:57Z","timestamp":1625493477000},"page":"1563-1568","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The effect of socioeconomic deprivation on presentation stage and long\u2010term outcomes in patients undergoing colorectal cancer resection in Western Sydney"],"prefix":"10.1111","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5630-9961","authenticated-orcid":false,"given":"Ewan","family":"MacDermid","sequence":"first","affiliation":[{"name":"Northern Clinical School University of Sydney  Sydney New South Wales Australia"},{"name":"Department of Surgery Nepean Hospital  Penrith New South Wales 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