{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:40:05Z","timestamp":1747183205660,"version":"3.40.5"},"reference-count":38,"publisher":"Wiley","issue":"1-2","license":[{"start":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T00:00:00Z","timestamp":1633996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To examine the outcome of patients treated with complete mesocolic excision (CME) with central vascular ligation (CVL) after conventional and laparoscopic surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively evaluated stage I\u2013IV colon adenocarcinoma patients treated by the same surgeon (L.M.) from 2013 to 2018. Postoperative complications, recurrences and survival are assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010one patients (M\/F: 24\/27) underwent laparoscopic right hemicolectomy with CME (L\u2010CME) or open CME (O\u2010CME) plus CVL. Tumour location was the caecum in 39.2% of cases, the transverse in 23.5%, the hepatic colonic flexure in 21.5%, and the ascending colon in 15.6%. Twenty\u2010four patients underwent L\u2010CME while 27 underwent O\u2010CME. More than 15 harvested lymphnodes are reported in 74.1% of O\u2010CME patients and in 66.7% of L\u2010CME patients (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.562). Postoperative complications occurred in 7 O\u2010CME and 5\u00a0L\u2010CME patients, respectively (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.669). Three\u2010year overall survival, including stage IV, was of 75% versus 77.8% for L\u2010CME and O\u2010CME patients, respectively, while for stage I\u2013III, was of 88.9% vs. 80% in L\u2010CME and O\u2010CME, respectively (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.440). The median follow\u2010up was of 2.43\u2009years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>CME with CVL is a meticulous, complex but feasible technique. In our experience, oncological results in terms of recurrences and overall survival, after conventional and laparoscopic CME plus CVL, are comparable. Patients with stage I\u2013III colon adenocarcinoma have a better prognostic trend especially when more than 15 lymphnodes are removed. The respect of oncological radicality and the correct indication to minimally invasive surgery are the undiscussed key outcome variables.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.17264","type":"journal-article","created":{"date-parts":[[2021,10,16]],"date-time":"2021-10-16T04:44:20Z","timestamp":1634359460000},"page":"132-139","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Laparoscopic and open complete mesocolic excision with central vascular ligation for right colonic adenocarcinoma: a retrospective comparative study"],"prefix":"10.1111","volume":"92","author":[{"given":"Domenica Carmen","family":"Testa","sequence":"first","affiliation":[{"name":"Department of Medical, Oral and Biotechnological Sciences \"G. d'Annunzio\" University  Chieti Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenzo","family":"Mazzola","sequence":"additional","affiliation":[{"name":"Department of Medical, Oral and Biotechnological Sciences \"G. d'Annunzio\" University  Chieti Italy"},{"name":"Unit of General Surgery \u201cRenzetti\u201d Hospital  Lanciano Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"di Martino","sequence":"additional","affiliation":[{"name":"Department of Medicine and Aging Sciences \u201cG. d'Annunzio\u201d University  Chieti Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Cotellese","sequence":"additional","affiliation":[{"name":"Department of Medical, Oral and Biotechnological Sciences \"G. d'Annunzio\" University  Chieti Italy"},{"name":"Fondazione Villa Serena per la Ricerca  Pescara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7947-5687","authenticated-orcid":false,"given":"Federico","family":"Selvaggi","sequence":"additional","affiliation":[{"name":"Department of Medical, Oral and Biotechnological Sciences \"G. d'Annunzio\" University  Chieti Italy"},{"name":"Unit of General Surgery \u201cRenzetti\u201d Hospital  Lanciano Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,10,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1515\/iss-2017-0042"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-017-2917-2"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3393\/ac.2017.08.05"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0218829"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-016-1710-9"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ans.14493"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.21037\/jgo.2019.05.01"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2020.09.007"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-021-03891-0"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-020-03797-3"},{"key":"e_1_2_9_12_1","first-page":"727","article-title":"Prognostic clinical and anatomopathological factors in surgery of carcinoma of the right colon","volume":"52","author":"Erba M","year":"1997","journal-title":"Minerva Chir."},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-004-9068-6"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2008.01735.x"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.24.1448"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-012-2294-4"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-017-1236-y"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-017-5970-6"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2016.10.005"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.05.062"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-013-1818-2"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-017-5982-2"},{"key":"e_1_2_9_23_1","first-page":"688","article-title":"Is complete mesocolic excision oncologically superior to conventional surgery for colon cancer? 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