{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T05:35:46Z","timestamp":1757309746967,"version":"3.40.5"},"reference-count":88,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T00:00:00Z","timestamp":1659484800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cystic fibrosis (CF) is a complex multiorgan disease, which often affects the gastrointestinal tract. With improved CF specific therapies and multidisciplinary management, patients with CF are now living longer with a median life expectancy of around 50\u2009years. This increased life expectancy has resulted in corresponding increase in presentations of the CF patient with comorbid surgical conditions that were never important considerations. Investigations and management of these conditions, such as distal intestinal obstruction syndrome and colorectal cancer warrant good clinical understanding of the unique challenges that CF patients present including chronic immunosuppression, impaired respiratory function and their multi\u2010organ dysfunction. The purpose of this review is to provide general surgeons with a contemporary update on the CF related surgical issues as they are likely to become increasingly involved in the care of these complex patients and form an integral part of the multidisciplinary team.<\/jats:p>","DOI":"10.1111\/ans.17948","type":"journal-article","created":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T13:29:13Z","timestamp":1659533353000},"page":"2425-2432","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Surgical considerations in cystic fibrosis: what every general surgeon needs to know"],"prefix":"10.1111","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8947-9817","authenticated-orcid":false,"given":"John D.","family":"Chetwood","sequence":"first","affiliation":[{"name":"AW Morrow Gastroenterology and Liver Centre Royal Prince Alfred Hospital  Sydney New South Wales Australia"},{"name":"Sydney Medical School University of Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anastasia","family":"Volovets","sequence":"additional","affiliation":[{"name":"AW Morrow Gastroenterology and Liver Centre Royal Prince Alfred Hospital  Sydney New South Wales Australia"},{"name":"Sydney Medical School University of Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheila","family":"Sivam","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Sleep Medicine Royal Prince Alfred Hospital  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2547-0204","authenticated-orcid":false,"given":"Cherry","family":"Koh","sequence":"additional","affiliation":[{"name":"Surgical Outcomes Research Centre (SOuRCe) Royal Prince Alfred Hospital  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,8,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000357646"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-008-0693-2"},{"volume-title":"Australian Cystic Fibrosis Data Registry Annual Report 2020","year":"2020","author":"Australian Cystic Fibrosis Data Registry","key":"e_1_2_10_4_1"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-63590-8"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(19)30337-6"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3181a6e01d"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jada.2008.02.020"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjaceaccp\/mkr038"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-2934"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X9502300310"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/ans.15357"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3181b845d0"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27431"},{"key":"e_1_2_10_15_1","first-page":"330","article-title":"Preoperative elective transjugular intrahepatic portosystemic shunt for cirrhotic patients undergoing abdominal surgery","volume":"31","author":"Jain D","year":"2018","journal-title":"Ann. Gastroenterol."},{"key":"e_1_2_10_16_1","first-page":"171","article-title":"Late intestinal obstruction in patients surviving neonatal meconium ileus","volume":"103","author":"Graham WP","year":"1965","journal-title":"Calif. Med."},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2017.06.013"},{"key":"e_1_2_10_18_1","first-page":"30181","article-title":"Changing paradigms in the treatment of gastrointestinal complications of cystic fibrosis in the era of cystic fibrosis transmembrane conductance regulator modulators","volume":"1526","author":"Konrad J","year":"2020","journal-title":"Paediatr. Respir. Rev."},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-021-04011-4"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199502233320803"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2012.11.006"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1569-1993(11)60005-2"},{"key":"e_1_2_10_23_1","first-page":"CD012798","article-title":"Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis","volume":"8","author":"Green J","year":"2018","journal-title":"Cochrane Database Syst. Rev."},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prrv.2016.04.001"},{"key":"e_1_2_10_25_1","first-page":"CD004651","article-title":"Oral water soluble contrast for the management of adhesive small bowel obstruction","volume":"2007","author":"Abbas S","year":"2007","journal-title":"Cochrane Database Syst. Rev."},{"volume-title":"Nutrition Guidelines for Cystic Fibrosis in Australia and New Zealand","year":"2017","author":"Saxby N","key":"e_1_2_10_26_1"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.51.2.285"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2016.02.002"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.14309\/crj.2018.53"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1258\/jrsm.2012.12s008"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.55.7.544"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-011-1790-z"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/95.5.381"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2011.05.003"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(90)90186-D"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(84)80029-3"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2321030363"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2016.01.002"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1914912117"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2015.483"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2017.12.012"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000000034"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20120562"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2005.03.106"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2017.07.007"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2012.07.019"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365528809090232"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201401-044FR"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.12020"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-005-0049-2"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2007.03.030"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.22630"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2007.06.003"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.118.4.1214"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-0012.2003.00060.x"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2004.04.044"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/738203"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2012.09.002"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(93)91085-V"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI116966"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2017.07.006"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.16.4.8835977"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/5128760"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-005-0053-6"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840140505"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.suc.2008.07.009"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.1295"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1007\/s005340050027"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(18)30188-8"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1993.tb12754.x"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.5772\/1439"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1007\/112_2015_5002"},{"key":"e_1_2_10_73_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-1764"},{"key":"e_1_2_10_74_1","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2002.37042"},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0b013e3282f36d04"},{"key":"e_1_2_10_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2017.07.004"},{"key":"e_1_2_10_77_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2010.09.046"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201304-0733OC"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2014.11.002"},{"key":"e_1_2_10_80_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-005-0059-z"},{"key":"e_1_2_10_81_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004376"},{"key":"e_1_2_10_82_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199809033391001"},{"key":"e_1_2_10_83_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2007.03.065"},{"key":"e_1_2_10_84_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPA.0000000000001350"},{"key":"e_1_2_10_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pan.2019.09.014"},{"key":"e_1_2_10_86_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/75.6.1005"},{"key":"e_1_2_10_87_1","first-page":"5321785","article-title":"Pancreatic cystosis in two adolescents with cystic fibrosis","volume":"2016","author":"Hatziagorou E","year":"2016","journal-title":"Case Rep. Pediatr."},{"key":"e_1_2_10_88_1","first-page":"101018","article-title":"Pancreatic cystosis in cystic fibrosis: sometimes a bike ride can help you decide","volume":"5","author":"Di Paolo M","year":"2020","journal-title":"Respir. Med. Case. Rep."},{"key":"e_1_2_10_89_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2007.125278"}],"container-title":["ANZ Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.17948","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ans.17948","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.17948","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T08:09:26Z","timestamp":1692691766000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ans.17948"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,3]]},"references-count":88,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1111\/ans.17948"],"URL":"https:\/\/doi.org\/10.1111\/ans.17948","archive":["Portico"],"relation":{},"ISSN":["1445-1433","1445-2197"],"issn-type":[{"type":"print","value":"1445-1433"},{"type":"electronic","value":"1445-2197"}],"subject":[],"published":{"date-parts":[[2022,8,3]]},"assertion":[{"value":"2022-05-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}