{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T17:22:39Z","timestamp":1790011359722,"version":"4.0.1"},"reference-count":33,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T00:00:00Z","timestamp":1659916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100016052","name":"Friends of The Mater Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100016052","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To determine the prevalence of opioid use in Australian hip (THA) or knee (TKA) cohort, and its association with outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>About 837 primary THA or TKA subjects prospectively completed Oxford Scores, and Knee or Hip Osteoarthritis Outcomes Score(KOOS\/HOOS) and opioid use in the previous week before arthroplasty. Subjects repeated the baseline survey at 6\u00a0months, with additional questions regarding satisfaction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Opioid use was reported by 19% preoperatively and 7% at 6\u00a0months. Opioid use was 46% at 6\u2009weeks and 10% at 6\u00a0months after TKR, and 16% at 6\u2009weeks and 4% at 6\u00a0months after THR. Preoperative opioid use was associated with back pain(OR 2.2, <jats:italic>P<\/jats:italic>\u00a0=\u20090.006), anxiety or depression(OR 1.8, <jats:italic>P<\/jats:italic>\u00a0=\u20090.001) and Oxford knee scores &lt;30(OR 5.6, <jats:italic>P<\/jats:italic>\u00a0=\u20090.021) in TKA subjects, and females in THA subjects(OR 1.7, <jats:italic>P<\/jats:italic>\u00a0=\u20090.04). There was no difference between preoperative opioid users and non\u2010users for satisfaction, or KOOS or HOOS scores at 6\u00a0months. 77% of patients taking opioids before surgery had ceased by 6\u00a0months, and 3% of preoperative non users reported opioid use at 6\u00a0months. Opioid use at 6\u00a0months was associated with preoperative use (OR 6.6\u201314.7, <jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001), and lower 6\u00a0month oxford scores (OR 4.4\u201383.6, <jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>One in five used opioids before arthroplasty. Pre\u2010operative opioid use was the strongest risk factor for opioid use at 6\u00a0months, increasing odds 7\u201315 times. Prolonged opioid use was rarely observed in the opioid na\u00efve (&lt;5% TKA and 1% THA). Preoperative opioid use was not associated with inferior outcomes or satisfaction.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.17969","type":"journal-article","created":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T09:20:16Z","timestamp":1659950416000},"page":"2261-2268","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Opioid use and patient outcomes in an Australian hip and knee arthroplasty cohort"],"prefix":"10.1111","volume":"92","author":[{"given":"Phil","family":"Huang","sequence":"first","affiliation":[{"name":"North Sydney Orthopaedic Research Group  Sydney New South Wales Australia"},{"name":"Orthopaedic Services The Mater Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack","family":"Brownrigg","sequence":"additional","affiliation":[{"name":"School of Medicine University of Notre Dame  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Roe","sequence":"additional","affiliation":[{"name":"North Sydney Orthopaedic Research Group  Sydney New South Wales Australia"},{"name":"North Sydney Orthopaedic and Sports Medicine Centre  Sydney New South Wales Australia"},{"name":"School of Clinical Medicine, Faculty of Medicine and Health UNSW  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Carmody","sequence":"additional","affiliation":[{"name":"North Sydney Orthopaedic Research Group  Sydney New South Wales Australia"},{"name":"North Sydney Orthopaedic and Sports Medicine Centre  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2685-5109","authenticated-orcid":false,"given":"Leo","family":"Pinczewski","sequence":"additional","affiliation":[{"name":"North Sydney Orthopaedic Research Group  Sydney New South Wales Australia"},{"name":"School of Medicine University of Notre Dame  Sydney New South Wales Australia"},{"name":"North Sydney Orthopaedic and Sports Medicine Centre  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Gooden","sequence":"additional","affiliation":[{"name":"North Sydney Orthopaedic Research Group  Sydney New South Wales Australia"},{"name":"North Sydney Orthopaedic and Sports Medicine Centre  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Lyons","sequence":"additional","affiliation":[{"name":"North Sydney Orthopaedic Research Group  Sydney New South Wales Australia"},{"name":"North Sydney Orthopaedic and Sports Medicine Centre  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0548-8573","authenticated-orcid":false,"given":"Lucy","family":"Salmon","sequence":"additional","affiliation":[{"name":"North Sydney Orthopaedic Research Group  Sydney New South Wales Australia"},{"name":"School of Medicine University of Notre Dame  Sydney New South Wales Australia"},{"name":"North Sydney Orthopaedic and Sports Medicine Centre  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7492-0577","authenticated-orcid":false,"given":"Ka","family":"Martina","sequence":"additional","affiliation":[{"name":"North Sydney Orthopaedic Research Group  Sydney New South Wales Australia"},{"name":"Orthopaedic Services The Mater Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Crighton","sequence":"additional","affiliation":[{"name":"Orthopaedic Services The Mater Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"O'Sullivan","sequence":"additional","affiliation":[{"name":"North Sydney Orthopaedic Research Group  Sydney New South Wales Australia"},{"name":"North Sydney Orthopaedic and Sports Medicine Centre  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,8,8]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"1736","article-title":"Global, regional, and national age\u2010sex\u2010specific mortality for 282 causes of death in 195 countries and territories, 1980\u20102017","volume":"392","author":"Collaborators GCoD","year":"2018","journal-title":"Lancet"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2020.108350"},{"key":"e_1_2_8_4_1","unstructured":"Substance Abuse and Mental Health Services Administration.Key substance use and mental health indicators in the United States: Results from the 2019 National Survey on Drug Use and Health (HHS Publication No. PEP20\u201007\u201001\u2010001). 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