{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:39:33Z","timestamp":1747183173518,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,9,19]],"date-time":"2022-09-19T00:00:00Z","timestamp":1663545600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Accurate staging for rectal cancer is pertinent with recent introduction of rectum\u2010sparing approaches for patients showing complete clinical response on restaging. Positron emission tomography(PET) is used in detection of recurrence or metastasis, but its value in routine preoperative rectal cancer staging remains unclear. Studies report that preoperative PET altered the stage in 39% and changed the management in 17\u201327% of patients. Our study aims to look at the utility of PET in routine preoperative staging of rectal cancer within 2 two colorectal units, and to determine if PET did result in a change in management.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients in Nepean Hospital (NSW) and Peter MacCallum Cancer Centre (VIC) who were diagnosed with rectal cancer between 1 January 2017 and 31 December 2021 were included in this retrospective study. All patients who did not have a PET scan were excluded. PET scan results were then compared with MRI and CT results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three hundred and fifty\u2010seven patients were included in the study. 30.3% of the patients had Stage 3 rectal cancer. 71.7% received neoadjuvant therapy. PET scan provided additional information in 55.5% of patients when compared with CT and MRI alone; 18.2% of the PET findings resulted in an altered management for the patient.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>PET scan can be a valuable tool in accurate staging, especially for ambiguous or equivocal lesions on CT. Our study demonstrated that additional information from PET scan resulted in an altered management plan in 18.2% of the patients. PET\/MRI as a newer modality may be more accurate with reduced radiation exposure.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.18058","type":"journal-article","created":{"date-parts":[[2022,9,19]],"date-time":"2022-09-19T07:18:15Z","timestamp":1663571895000},"page":"617-621","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Retrospective audit: Utility of <scp>PET<\/scp> scan in routine preoperative rectal cancer staging"],"prefix":"10.1111","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9548-9720","authenticated-orcid":false,"given":"Michelle Zhiyun","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery Nepean Hospital  Kingswood New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinyi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Nepean Hospital  Kingswood New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1507-8228","authenticated-orcid":false,"given":"Milton","family":"Mui","sequence":"additional","affiliation":[{"name":"Division of Cancer Surgery Peter MacCallum Cancer Centre  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1392-2480","authenticated-orcid":false,"given":"Joseph C. H.","family":"Kong","sequence":"additional","affiliation":[{"name":"Division of Cancer Surgery Peter MacCallum Cancer Centre  Melbourne Victoria Australia"},{"name":"Division of Cancer Research Peter MacCallum Cancer Centre  Melbourne Victoria Australia"},{"name":"Sir Peter MacCallum Department of Oncology University of Melbourne  Parkville Victoria Australia"},{"name":"Department of Surgery Central Clinical School, Monash University, The Alfred Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9846-8776","authenticated-orcid":false,"given":"Alexander G.","family":"Heriot","sequence":"additional","affiliation":[{"name":"Division of Cancer Surgery Peter MacCallum Cancer Centre  Melbourne Victoria Australia"},{"name":"Division of Cancer Research Peter MacCallum Cancer Centre  Melbourne Victoria Australia"},{"name":"Sir Peter MacCallum Department of Oncology University of Melbourne  Parkville Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jodie","family":"Ellis\u2010Clark","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Nepean Hospital  Kingswood New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,9,19]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_8_2_1","DOI":"10.1007\/s12149-021-01580-0"},{"doi-asserted-by":"publisher","key":"e_1_2_8_3_1","DOI":"10.3748\/wjg.v17.i7.828"},{"doi-asserted-by":"publisher","key":"e_1_2_8_4_1","DOI":"10.1245\/ASO.2006.04.042"},{"doi-asserted-by":"publisher","key":"e_1_2_8_5_1","DOI":"10.2214\/AJR.18.19620"},{"doi-asserted-by":"publisher","key":"e_1_2_8_6_1","DOI":"10.2967\/jnumed.114.141838"},{"doi-asserted-by":"publisher","key":"e_1_2_8_7_1","DOI":"10.1007\/s10350-003-0089-3"},{"doi-asserted-by":"publisher","key":"e_1_2_8_8_1","DOI":"10.1097\/MNM.0b013e328357b2d9"},{"doi-asserted-by":"publisher","key":"e_1_2_8_9_1","DOI":"10.1007\/s00261-019-02089-x"},{"doi-asserted-by":"publisher","key":"e_1_2_8_10_1","DOI":"10.5217\/ir.2017.15.2.208"},{"doi-asserted-by":"publisher","key":"e_1_2_8_11_1","DOI":"10.1055\/a-1266-3308"},{"doi-asserted-by":"publisher","key":"e_1_2_8_12_1","DOI":"10.1097\/RCT.0b013e318225720f"},{"doi-asserted-by":"publisher","key":"e_1_2_8_13_1","DOI":"10.1007\/s00259-015-3137-z"},{"doi-asserted-by":"publisher","key":"e_1_2_8_14_1","DOI":"10.1016\/S0002-9610(00)00406-2"},{"doi-asserted-by":"publisher","key":"e_1_2_8_15_1","DOI":"10.1007\/s00261-015-0474-0"},{"key":"e_1_2_8_16_1","first-page":"21773","article-title":"Pre\u2010operative TNM staging of primary colorectal cancer by (18)F\u2010FDG PET\u2010CT or PET: a meta\u2010analysis including 2283 patients","volume":"8","author":"Ye Y","year":"2015","journal-title":"Int. J. Clin. Exp. Med."},{"doi-asserted-by":"publisher","key":"e_1_2_8_17_1","DOI":"10.1097\/RLU.0000000000000812"},{"key":"e_1_2_8_18_1","first-page":"1784","article-title":"Routine (18)F\u2010FDG PET preoperative staging of colorectal cancer: comparison with conventional staging and its impact on treatment decision making","volume":"44","author":"Kantorov\u00e1 I","year":"2003","journal-title":"J. Nucl. Med"},{"key":"e_1_2_8_19_1","first-page":"492","article-title":"The clinical impact of (18)F\u2010FDG PET in patients with suspected or confirmed recurrence of colorectal cancer: a prospective study","volume":"43","author":"Kalff V","year":"2002","journal-title":"J. Nucl. Med."},{"doi-asserted-by":"publisher","key":"e_1_2_8_20_1","DOI":"10.1002\/jmri.25337"},{"doi-asserted-by":"publisher","key":"e_1_2_8_21_1","DOI":"10.2214\/AJR.14.13818"},{"doi-asserted-by":"publisher","key":"e_1_2_8_22_1","DOI":"10.1148\/radiol.2019190794"},{"doi-asserted-by":"publisher","key":"e_1_2_8_23_1","DOI":"10.1007\/s00259-020-04911-x"},{"doi-asserted-by":"publisher","key":"e_1_2_8_24_1","DOI":"10.1002\/jmri.25711"},{"doi-asserted-by":"publisher","key":"e_1_2_8_25_1","DOI":"10.1186\/s40644-019-0237-1"}],"container-title":["ANZ Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.18058","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ans.18058","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.18058","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T19:56:47Z","timestamp":1692647807000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ans.18058"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,19]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["10.1111\/ans.18058"],"URL":"https:\/\/doi.org\/10.1111\/ans.18058","archive":["Portico"],"relation":{},"ISSN":["1445-1433","1445-2197"],"issn-type":[{"type":"print","value":"1445-1433"},{"type":"electronic","value":"1445-2197"}],"subject":[],"published":{"date-parts":[[2022,9,19]]},"assertion":[{"value":"2022-08-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}