{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T07:14:31Z","timestamp":1792739671649,"version":"4.5.0"},"reference-count":99,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,12,18]],"date-time":"2022-12-18T00:00:00Z","timestamp":1671321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Traditionally, international guidelines recommend patients with acute diverticulitis should be followed up with a colonoscopy 6\u20138\u2009weeks after discharge. However, the need for an interval colonoscopy has been increasingly challenged in the setting of computed tomography (CT). Previous meta\u2010analyses have included studies which combined suspected rather than imaging confirmed diverticulitis and often without correlation with endoscopic findings. This meta\u2010analysis aims to investigate endoscopic findings of patients with CT confirmed diverticulitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An electronic search of Medline, PubMed, Cochrane Library, Embase, CINAHL, Web of Science, Scopus, Clinicaltrials.gov and WHO ICTRP was performed up to October 18, 2021. Studies which reported CT confirmed acute diverticulitis in adults and who underwent endoscopic follow\u2010up with either a colonoscopy or flexible sigmoidoscopy were included. Studies were excluded if diverticulitis was diagnosed by clinical grounds alone, ultrasound, barium enema, or other non\u2010CT forms of imaging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 68 studies with 13\u2009905 patients were included. Median age was 58\u2009years and male to female ratio was 0.84. Cancer was detected in 2.0% and advanced adenoma in 3.8%. Complicated diverticulitis had 9.2 higher odds of cancer compared to uncomplicated diverticulitis (95% CI 4.42\u201319.08, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Adenomas were detected in 17%. Of those diagnosed with colorectal cancer, 85% were concordant with the site of the diverticulitis on CT while 15% were incidental findings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Routine colonoscopic follow up should be recommended in medically fit patients who have CT proven acute diverticulitis due to the higher than population prevalence of colorectal cancer and advanced adenomas.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.18190","type":"journal-article","created":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T04:55:07Z","timestamp":1671425707000},"page":"1150-1158","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Endoscopic findings after <scp>CT<\/scp> proven acute diverticulitis: a systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9339-6355","authenticated-orcid":false,"given":"Amy Millicent Yesheng","family":"Cao","sequence":"first","affiliation":[{"name":"Department of Surgery Macquarie University Hospital  Sydney New South Wales Australia"},{"name":"Macquarie Medical School, Faculty of Medicine, Health and Human Sciences Macquarie University  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5566-4769","authenticated-orcid":false,"given":"Vincent Wai","family":"Lam","sequence":"additional","affiliation":[{"name":"Department of Surgery Macquarie University Hospital  Sydney New South Wales Australia"},{"name":"Macquarie Medical School, Faculty of Medicine, Health and Human Sciences Macquarie University  Sydney New South Wales Australia"},{"name":"Department of Hepatobiliary Surgery Westmead Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3724-1698","authenticated-orcid":false,"given":"Matthew John Francis Xavier","family":"Rickard","sequence":"additional","affiliation":[{"name":"Department of Surgery Macquarie University Hospital  Sydney New South Wales Australia"},{"name":"Discipline of Surgery, School of Medicine, Faculty of Medicine and Health University of Sydney  Sydney New South Wales Australia"},{"name":"Division of Colorectal Surgery, Department of Surgery Concord Repatriation General Hospital  Sydney New South Wales Australia"},{"name":"Department of Surgery Macquarie University Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,12,18]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-016-3480-7"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-015-4093-1"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.176.1.2191360"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000075"},{"key":"e_1_2_9_6_1","first-page":"23","article-title":"A systematic review on the role of colonoscopy after CT\u2010proven left\u2010sided acute diverticulitis","volume":"20","author":"Rottier SJ","year":"2018","journal-title":"Color. 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