{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T12:29:34Z","timestamp":1751545774929,"version":"3.40.5"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T00:00:00Z","timestamp":1674777600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010455","name":"Swiss Transplant Cohort Study","doi-asserted-by":"publisher","award":["FUP 162"],"award-info":[{"award-number":["FUP 162"]}],"id":[{"id":"10.13039\/501100010455","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We analysed the impact of perceived liver donor quality on transplant recipient outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>this prospective cohort study included all deceased liver donors during 2008\u20132018 in the Swiss Transplant Cohort Study. Perceived low\u2010quality liver donors were defined when refused for \u22655 top listed recipients or for all recipients in at least one centre before being transplanted. The effect of liver donor quality on relisting or recipient death at 1\u00a0week and 1\u00a0year after transplantation was analysed using Kaplan\u2013Meier and Cox proportional hazard models. A 1:3 matching was also performed using a recipient score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 973 liver donors, 187 (19.2%) had perceived poor\u2010quality. Males, obesity, donation after circulatory death and alanine aminotransferase values were significantly associated with perceived poor\u2010quality, with no significant effect of the perceived quality on re\u2010listing or death within the first week and first year post\u2010transplant [(aHR)\u00a0=\u00a01.45, 95% CI: (0.6, 3.5), <jats:italic>P<\/jats:italic>\u00a0=\u20090.41 and aHR\u00a0=\u00a01.52 (95% CI 0.98\u20132.35), <jats:italic>P<\/jats:italic>\u00a0=\u20090.06], adjusting by recipient age and gender, obesity, diabetes, prior liver transplantation and model for end\u2010stage liver disease (MELD) score. At 1\u00a0year, prior liver transplantation and higher MELD score associated with higher risk of re\u2010listing or death.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Comparable post\u2010transplant outcomes with different perceived quality liver donors stresses the need to improve donor selection in liver transplantation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.18217","type":"journal-article","created":{"date-parts":[[2023,1,28]],"date-time":"2023-01-28T07:14:31Z","timestamp":1674890071000},"page":"918-925","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The impact of perceived donor liver quality on post\u2010transplant outcome"],"prefix":"10.1111","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9083-3561","authenticated-orcid":false,"given":"Melisa","family":"Dirchwolf","sequence":"first","affiliation":[{"name":"Novartis Fellowship in Hepatology, Department of Biomedical Research University of Bern  Bern Switzerland"},{"name":"Liver Unit Hospital Privado de Rosario  Santa Fe Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8262-0304","authenticated-orcid":false,"given":"Chiara","family":"Becchetti","sequence":"additional","affiliation":[{"name":"Hepatology, Department of Biomedical Research University of Bern  Bern Switzerland"},{"name":"Department of Visceral Surgery and Medicine, Inselspital University Hospital Bern, University of Bern  Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3399-5078","authenticated-orcid":false,"given":"Susanne","family":"Stampf","sequence":"additional","affiliation":[{"name":"Clinic for Transplantation Immunology and Nephrology University Hospital Basel  Basel Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christa","family":"Haldimann","sequence":"additional","affiliation":[{"name":"Department of Visceral Surgery and Medicine, Inselspital University Hospital Bern, University of Bern  Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2921-4147","authenticated-orcid":false,"given":"Franz","family":"Immer","sequence":"additional","affiliation":[{"name":"Swisstransplant The Swiss National Foundation for Organ Donation and Transplantation  Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franziska","family":"Beyeler","sequence":"additional","affiliation":[{"name":"Swisstransplant The Swiss National Foundation for Organ Donation and Transplantation  Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1652-4522","authenticated-orcid":false,"given":"Christian","family":"Toso","sequence":"additional","affiliation":[{"name":"Abdominal Surgery Geneva University Hospital of Geneva  Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3016-604X","authenticated-orcid":false,"given":"Philipp","family":"Dutkowski","sequence":"additional","affiliation":[{"name":"Abdominal Transplant Surgery University Hospital of Z\u00fcrich  Z\u00fcrich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9924-1749","authenticated-orcid":false,"given":"Daniel","family":"Candinas","sequence":"additional","affiliation":[{"name":"Department of Visceral Surgery and Medicine, Inselspital University Hospital Bern, University of Bern  Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8062-1346","authenticated-orcid":false,"given":"Jean\u2010Francois","family":"Dufour","sequence":"additional","affiliation":[{"name":"Hepatology, Department of Biomedical Research University of Bern  Bern Switzerland"},{"name":"Centre des Maladies Digestives  Lausanne Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4887-5776","authenticated-orcid":false,"given":"Vanessa","family":"Banz","sequence":"additional","affiliation":[{"name":"Department of Visceral Surgery and Medicine, Inselspital University Hospital Bern, University of Bern  Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the Swiss Transplant Cohort Study","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,1,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.24160"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.25320"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v24.i23.2441"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2020.05.024"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21668"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000002069"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/08941939.2018.1517197"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000003052"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2018.5568"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2015.12.053"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.24799"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-012-9754-y"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hpb.2021.12.009"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/pan\/mpl013"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v042.i08"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2006.01242.x"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2017.10.034"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365521.2010.510577"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.14046"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhepr.2020.100118"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000002127"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2009.01109.x"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-019-05271-w"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/08941939.2018.1542048"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2008.02165.x"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000005110"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.02086.x"}],"container-title":["ANZ Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.18217","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ans.18217","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.18217","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T19:56:10Z","timestamp":1692734170000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ans.18217"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,27]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1111\/ans.18217"],"URL":"https:\/\/doi.org\/10.1111\/ans.18217","archive":["Portico"],"relation":{},"ISSN":["1445-1433","1445-2197"],"issn-type":[{"type":"print","value":"1445-1433"},{"type":"electronic","value":"1445-2197"}],"subject":[],"published":{"date-parts":[[2023,1,27]]},"assertion":[{"value":"2022-08-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}