{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T15:54:08Z","timestamp":1770911648585,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T00:00:00Z","timestamp":1672185600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100024053","name":"Sydney Local Health District","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100024053","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There is limited information regarding the number of patients with diabetes\u2010related foot ulceration (DFU) who receive minor or major amputation, and how quickly these amputations occur. This study aimed to identify the incidence of index minor and major amputation among inpatients with DFU over 4\u2009years, and where amputation occurred during the patient's index DFU\u2010related admission, investigate prognostic factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The incidence of index minor and major amputation, and the admission sequence during which amputation occurred were identified from DFU\u2010related admissions to two public hospitals during 2014\u20132018. Where minor or major amputation occurred during the patient's index DFU\u2010related admission, prognostic factors were investigated using logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>DFU\u2010related hospital admissions were required by 564 patients. The incidence of minor amputation over 4\u2009years was 34% (<jats:italic>n<\/jats:italic>\u00a0=\u2009193). The incidence of minor amputation during the patient's index DFU\u2010related admission was 28% (<jats:italic>n<\/jats:italic>\u00a0=\u2009155), which was associated with requiring revascularisation (odds ratio [OR] 2.33, 95% CI 1.53\u20133.55, <jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001). The incidence of major amputation over 4\u2009years was 8% (<jats:italic>n<\/jats:italic>\u00a0=\u200945). The incidence of major amputation during the patient's index DFU\u2010related admission was 6% (<jats:italic>n<\/jats:italic>\u00a0=\u200931), which was associated with having more comorbidities (OR 1.58, 95% CI 1.10\u20132.26, <jats:italic>P<\/jats:italic>\u00a0=\u20090.01) and receiving care for a mental health condition (OR 3.85, 95% CI 1.48\u201310.01, <jats:italic>P<\/jats:italic>\u00a0=\u20090.006).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Most amputations occurred during the patient's index DFU\u2010related hospital admission. Major amputation during a patient's index admission was associated with more comorbidities and mental health conditions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.18224","type":"journal-article","created":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T11:41:37Z","timestamp":1672227697000},"page":"1510-1516","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Timing of minor and major amputation in patients with diabetes\u2010related foot ulceration admitted to two public tertiary referral hospitals in Australia"],"prefix":"10.1111","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0013-9507","authenticated-orcid":false,"given":"Sarah M.","family":"Manewell","sequence":"first","affiliation":[{"name":"School of Health Sciences, Faculty of Medicine and Health The University of Sydney  Sydney New South Wales Australia"},{"name":"Podiatry Department, Sydney Local Health District NSW Health  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6701-6213","authenticated-orcid":false,"given":"Sarah J.","family":"Aitken","sequence":"additional","affiliation":[{"name":"Vascular Department, Concord Repatriation General Hospital, Sydney Local Health District NSW Health  Sydney New South Wales Australia"},{"name":"Concord Clinical School, Faculty of Medicine and Health The University of Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa L.","family":"Nube","sequence":"additional","affiliation":[{"name":"Podiatry Department, Sydney Local Health District NSW Health  Sydney New South Wales Australia"},{"name":"High Risk Foot Service, Diabetes Centre, Royal Prince Alfred Hospital, Sydney Local Health District NSW Health  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna M.","family":"Crawford","sequence":"additional","affiliation":[{"name":"Podiatry Department, Sydney Local Health District NSW Health  Sydney New South Wales Australia"},{"name":"High Risk Foot Service, Diabetes Centre, Royal Prince Alfred Hospital, Sydney Local Health District NSW Health  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria I.","family":"Constantino","sequence":"additional","affiliation":[{"name":"High Risk Foot Service, Diabetes Centre, Royal Prince Alfred Hospital, Sydney Local Health District NSW Health  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen M.","family":"Twigg","sequence":"additional","affiliation":[{"name":"High Risk Foot Service, Diabetes Centre, Royal Prince Alfred Hospital, Sydney Local Health District NSW Health  Sydney New South Wales Australia"},{"name":"Central Clinical School, Faculty of Medicine and Health The University of Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hylton B.","family":"Menz","sequence":"additional","affiliation":[{"name":"School of Allied Health, Human Services and Sport La Trobe University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Sherrington","sequence":"additional","affiliation":[{"name":"Institute for Musculoskeletal Health, Faculty of Medicine and Health The University of Sydney\/Sydney Local Health District  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3593-1396","authenticated-orcid":false,"given":"Serene S.","family":"Paul","sequence":"additional","affiliation":[{"name":"School of Health Sciences, Faculty of Medicine and Health The University of Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,12,28]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/1520-7560(200009\/10)16:1 <::AID-DMRR139>3.0.CO;2-8"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3268"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2019.107996"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.2634"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.26.2.491"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0239236"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13047-017-0230-5"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc12-0200"},{"key":"e_1_2_10_10_1","unstructured":"Australian Institute of Health and Welfare.Australian hospital peer groups. 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