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This study was undertaken to describe the clinical, pathological and familial characteristics of patients with EOCRC and their oncological outcomes and compare this with previously published data on late onset colorectal cancer (LOCRC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective review of all patients diagnosed with EOCRC in Canterbury between 2010 and 2017 was conducted. Data was collected on demographics, family history, treatment, and oncologic outcomes. Kaplan\u2013Meier survival curves were calculated to assess overall survival based on disease stage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the study period (2010\u20132017) there were 3340 colorectal cancers diagnosed in Canterbury, of which 201 (6%) were in patients under 50\u2009years (range: 17\u201349). Of these, 87 (43.3%) were female and 125 (62.2%) were aged between 40 and 49\u2009years. 28 (13.9%) were associated with hereditary conditions. Of the 201 patients, 139 (69.2%) had rectal or left\u2010sided cancers. 142 (70.6%) patients presented with either stage 3 or 4 disease and the 5\u2010year overall survival by stage was 79.1% and 14.4%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>EOCRC is increasing and usually presents as distal left sided cancers, and often at an advanced stage. They do not appear to have the common risk factors of family history or inherited pre\u2010disposition for colorectal cancer. Planning by healthcare providers for this epidemiological change is imperative in investigating symptomatic patients under 50 and optimizing early detection and prevention.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.18357","type":"journal-article","created":{"date-parts":[[2023,2,28]],"date-time":"2023-02-28T12:39:35Z","timestamp":1677587975000},"page":"2148-2154","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Early onset colorectal cancer in Canterbury, New Zealand"],"prefix":"10.1111","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0037-9244","authenticated-orcid":false,"given":"Nasya","family":"Thompson","sequence":"first","affiliation":[{"name":"Department of Surgery University of Otago Christchurch  Christchurch New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grace","family":"Gatenby","sequence":"additional","affiliation":[{"name":"Department of Surgery Te Whatu Ora Health New Zealand Waitaha Canterbury  Christchurch New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4175-7603","authenticated-orcid":false,"given":"Oliver","family":"Waddell","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Otago Christchurch  Christchurch New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Purcell","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Otago Christchurch  Christchurch New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqui","family":"Keenan","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Otago Christchurch  Christchurch New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John F.","family":"Pearson","sequence":"additional","affiliation":[{"name":"Biostatistics and Computational Biology Unit University of Otago Christchurch  Christchurch New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francis","family":"Frizelle","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Otago Christchurch  Christchurch New Zealand"},{"name":"Department of Surgery Te Whatu Ora Health New Zealand Waitaha Canterbury  Christchurch New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamara","family":"Glyn","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Otago Christchurch  Christchurch New Zealand"},{"name":"Department of Surgery Te Whatu Ora Health New Zealand Waitaha Canterbury  Christchurch New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,28]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"SocietyAC.Colorectal cancer facts & figures 2020\u20102022. 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