{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:01:20Z","timestamp":1790694080173,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"7-8","license":[{"start":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T00:00:00Z","timestamp":1680134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T00:00:00Z","timestamp":1680134400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>In acute appendicitis, decision\u2010making around operative intervention for paediatric patients differs from adults due to a higher weight placed on clinical assessment and reduced rates of cross\u2010sectional imaging. In regional settings, non\u2010paediatric emergency doctors, general surgeons, and radiologists usually assess and manage this patient group. Differences have been observed in paediatric negative appendicectomy rates between general and paediatric centres.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective cohort study was performed, identifying paediatric patients undergoing emergency appendicectomy at the Southwest Health Campus (Bunbury, Western Australia) from 2017 to 2021. The primary outcome measure was histopathology confirming the absence of transmural inflammation of the appendix. In addition, clinical, biochemical and radiological data were collected to identify predictors of negative appendicectomy (NA). Secondary outcome measures were hospital length\u2010of\u2010stay and post\u2010operative complication rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Four hundred and twenty\u2010one patients were identified, of which 44.9% had a negative appendicectomy. Statistically significant associations between female gender, white cell count less than 10\u2009\u00d7\u200910\n                      <jats:sup>9<\/jats:sup>\n                      , neutrophil ratio less than 75%, low CRP and NA were observed. NA was not associated with a lower risk of re\u2010admission or complications compared with appendicectomy for appendicitis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our centre's NA rate is higher than that observed in the literature at both non\u2010paediatric and paediatric surgical centres. NA has similar morbidity risk to appendicectomy for uncomplicated appendicitis and offers a timely reminder that diagnostic laparoscopy in children is not benign.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ans.18446","type":"journal-article","created":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T11:45:51Z","timestamp":1680176751000},"page":"1987-1992","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Paediatric negative appendicectomy rates at a regional Western Australian Centre: a\n                    <scp>five\u2010year<\/scp>\n                    cohort study"],"prefix":"10.1111","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7023-242X","authenticated-orcid":false,"given":"Natasha","family":"Behrendorff","sequence":"first","affiliation":[{"name":"General Surgery Department, South West Health Campus Western Australia Country Health Service  Bunbury Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6116-5499","authenticated-orcid":false,"given":"Ranesh","family":"Palan","sequence":"additional","affiliation":[{"name":"General Surgery Department, South West Health Campus Western Australia Country Health Service  Bunbury Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommy","family":"McKitterick","sequence":"additional","affiliation":[{"name":"General Surgery Department, South West Health Campus Western Australia Country Health Service  Bunbury Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacinta","family":"Cover","sequence":"additional","affiliation":[{"name":"General Surgery Department, South West Health Campus Western Australia Country Health Service  Bunbury Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,3,30]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12262-010-0008-5"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1308\/003588412X13171221592131"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13017-020-00306-3"},{"key":"e_1_2_8_5_1","article-title":"Computed tomography for diagnosis of acute appendicitis in adults","volume":"2019","author":"Rud B","year":"2019","journal-title":"Cochrane Database Syst. Rev."},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2012.09.004"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-004-8866-1"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2008.06.004"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000246886.80424.ad"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1308\/003588414X13946184903801"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00068-019-01138-w"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2016.09.005"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs5.52"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2018.10.106"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2022.03.029"},{"key":"e_1_2_8_16_1","first-page":"29","article-title":"Paediatric appendicectomy in NSW: changes in practice over time and between groups","volume":"15","author":"Close GR","year":"1995","journal-title":"J. Qual. Clin. Pract."},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2018.05.014"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/pq9.0000000000000541"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2013.2517"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2008.10.086"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/000313481508100916"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2018.10.018"},{"key":"e_1_2_8_23_1","unstructured":"Australian Commission on Safety and Quality in Health Care.The Second Australian Atlas of Healthcare Variation\u20144.5 Appendicectomy 2017. [cited 2 May 2022.]https:\/\/www.safetyandquality.gov.au\/publications\u2010and\u2010resources\/resource\u2010library\/australian\u2010atlas\u2010healthcare\u2010variation\u20102017\u201045\u2010appendicectomy\u20100"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.45.5.456"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2012.06168.x"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2018.12.019"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-3375"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000001352"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9455"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2019.12.018"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(95)90556-1"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-2418"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-010-0285-9"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.12998"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-016-3990-2"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpag.2021.05.004"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20180585"}],"container-title":["ANZ Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.18446","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ans.18446","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.18446","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:34:59Z","timestamp":1790692499000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ans.18446"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,30]]},"references-count":36,"journal-issue":{"issue":"7-8","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["10.1111\/ans.18446"],"URL":"https:\/\/doi.org\/10.1111\/ans.18446","archive":["Portico"],"relation":{},"ISSN":["1445-1433","1445-2197"],"issn-type":[{"value":"1445-1433","type":"print"},{"value":"1445-2197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,30]]},"assertion":[{"value":"2022-12-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}