{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T07:25:44Z","timestamp":1773127544228,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,7,10]],"date-time":"2023-07-10T00:00:00Z","timestamp":1688947200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The incidence of incisional hernias (IH) after midline laparotomy varies from 11% to 20%. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS\u2010HIPEC) is potentially prone to hernias because a Xiphoid to pubis laparotomy incision performed on patients who have undergone previous abdominal surgeries with the addition of chemotherapy and its related adverse effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a retrospective analysis on a prospectively maintained single institution database from March 2015 to July 2020. The inclusion criteria were patients who underwent CRS\u2010HIPEC and had at least 6\u2009months postoperative follow\u2010up with post\u2010operative cross\u2010sectional imaging study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred and one patients were included in the study. All patients underwent CRS\u2010HIPEC with resection of previous scar and umbilectomy. Fifty\u2010four patients were diagnosed with IH (26.9%). The major risk factors for IH in multivariate analysis were higher American society of Anesthesiologists score (ASA) (OR 3.9, <jats:italic>P<\/jats:italic>\u2009=\u20090.012), increasing age (OR 1.06, <jats:italic>P<\/jats:italic>\u2009=\u20090.004) and increasing BMI (OR 1.1, <jats:italic>P<\/jats:italic>\u2009=\u20090.006). Most of the hernia sites were median (<jats:italic>n<\/jats:italic>\u2009=\u200943, 79.6%). Eleven (20.4%) patients had lateral hernias due to stoma incisions or drain sites. Most of the median hernias were at the level of the resected umbilicus 58.9% (<jats:italic>n<\/jats:italic>\u2009=\u200923). Five (9.3%) of the patients with IH necessitated an urgent surgical repair.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We have demonstrated that more than a quarter of the patients after CRS\u2010HIPEC suffer from IH and up to 10% of them may require surgical intervention. More research is needed to find the appropriate intraoperative interventions to minimize this sequela.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.18594","type":"journal-article","created":{"date-parts":[[2023,7,11]],"date-time":"2023-07-11T06:19:39Z","timestamp":1689056379000},"page":"2192-2196","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Increased risk for incisional hernia following cytoreductive surgery with hyperthermic intraperitoneal chemotherapy"],"prefix":"10.1111","volume":"93","author":[{"given":"Almog","family":"Ben\u2010Yaacov","sequence":"first","affiliation":[{"name":"General and Oncological Surgery Department C, Chaim Sheba Medical Center\u2014Affiliated to the Sackler Faculty of Medicine Tel Aviv University  Tel Hashomer Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shachar","family":"Laks","sequence":"additional","affiliation":[{"name":"General and Oncological Surgery 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