{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T01:45:36Z","timestamp":1778291136222,"version":"3.51.4"},"reference-count":16,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T00:00:00Z","timestamp":1704326400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011371","name":"Royal Australasian College of Surgeons","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011371","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>While endoscopic step\u2010up approach with delayed drainage (more than 28\u2009days from diagnosis) was shown to produce the best outcomes in the treatment of pancreatic walled\u2010off necrosis (WON), we assessed our single centre experience of early versus delayed endoscopic drainage of pancreatic necrotic collections.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who underwent endoscopic drainage of pancreatic necrotic collections between 2011 and 2022 under Monash Health were identified. They were excluded if below 18\u2009years old or their follow up data were missing. The included patients' medical records, pathology results, and imaging findings were retrospectively reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 60 patients were included. 31.58% required percutaneous drainage and 15% received either endoscopic or surgical necrosectomy. The disease related mortality was 8.47% and the average length of stay (LOS) was 70.92\u2009days. No significant difference was shown in disease\u2010related mortality (10.5% <jats:italic>vs.<\/jats:italic> 7.5%, <jats:italic>P<\/jats:italic>\u2009=\u20090.697) or LOS (75.35 <jats:italic>vs.<\/jats:italic> 68.7, <jats:italic>P<\/jats:italic>\u2009=\u20090.644) between early and delayed drainage cohorts, but patients who received early drainage have higher qSOFA score on the day of drainage (2 <jats:italic>vs.<\/jats:italic> 0, <jats:italic>P<\/jats:italic>\u2009=\u20090.004).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Repetitive endoscopic drainage with selective percutaneous drainage is effective in the management of pancreatic necrotic collections. Early drainage should be considered in patients who developed severe sepsis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.18852","type":"journal-article","created":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T10:35:15Z","timestamp":1704364515000},"page":"881-887","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Repetitive endoscopic drainage as initial intervention is safe and effective for early treatment of pancreatic necrotic collections"],"prefix":"10.1111","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2351-9537","authenticated-orcid":false,"given":"Yi","family":"Ma","sequence":"first","affiliation":[{"name":"Department of Upper GI and Hepatobiliary Surgery Monash Medical Centre  Clayton Victoria Australia"},{"name":"Department of Surgery The University of Melbourne  Heidelberg Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felicia","family":"Ong","sequence":"additional","affiliation":[{"name":"Department of Upper GI and Hepatobiliary Surgery Monash Medical Centre  Clayton Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Hew","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Monash Medical Centre  Clayton Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Swan","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Monash Medical Centre  Clayton Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Devonshire","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Monash Medical Centre  Clayton Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Croagh","sequence":"additional","affiliation":[{"name":"Department of Upper GI and Hepatobiliary Surgery Monash Medical Centre  Clayton Victoria Australia"},{"name":"Department of Surgery Monash University  Clayton Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,1,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2011.08.026"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.06.073"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1055\/a-0588-5365"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2012-302779"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32404-2"},{"key":"e_1_2_8_7_1","first-page":"454","article-title":"Is endoscopic drainage better than percutaneous drainage for patients with pancreatic fluid collections? A comparative meta\u2010analysis","volume":"113","author":"Cai QC","year":"2021","journal-title":"Rev. Esp. Enferm. Dig."},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pan.2021.06.006"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-019-06866-z"},{"key":"e_1_2_8_10_1","article-title":"Combined drainage and protocolized necrosectomy through a co\u2010axial lumen\u2010apposing metal stent for pancreatic walled\u2010off necrosis: a prospective multicenter trial","volume":"277","author":"Dayyeh BKA","year":"2021","journal-title":"Ann. 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