{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T23:00:01Z","timestamp":1774479601915,"version":"3.50.1"},"reference-count":60,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The decision for resection of adrenal metastasis from colorectal cancers remain controversial and there is no proposed standard treatment. The aim of the article is to review the available literature on outcomes and complications rates following adrenalectomy for adrenal metastasis from colorectal cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Relevant papers were identified through electronic databases. Data was extracted independently by two authors on a Microsoft Excel spreadsheet up to June 2023.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 55 studies were included in the final analysis (145 cases). A large proportion of patients had an uneventful postoperative recovery following surgical adrenalectomy. The mean length of follow up ranged from 2\u2009months to 9.5\u2009years. A total of 33 (22.8%) patients were alive and well with no evidence of local or systemic recurrence; 2 (1.4%) patients had recurrence in the bed of adrenalectomy; 2 (1.4%) patients were alive with recurrence in the contralateral adrenal gland; 4 (2.8%) patients were alive with extra\u2010adrenal metastasis, and 7 (4.8%) patients were alive and well with no comments regarding local and systemic recurrence. Post\u2010operative mortality following adrenalectomy was uncommon: 1 patient died due to systemic sepsis following anastomotic leak. 17.2% of patients died due to disease progression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>If complete resection can be achieved, surgical adrenalectomy in the surgically fit patient should be strongly considered, especially in patients with solitary adrenal metastasis which may translate into survival benefits and potential surgical cure.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.18923","type":"journal-article","created":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T10:25:14Z","timestamp":1709288714000},"page":"545-559","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Surgical resection of adrenal metastasis from colorectal cancers: a systematic review"],"prefix":"10.1111","volume":"94","author":[{"given":"Thi Ai Van Terresa","family":"Nguyen","sequence":"first","affiliation":[{"name":"Department of Colon &amp; Rectal Surgery Liverpool Hospital  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sze Ling","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of General Surgery Royal Perth Hospital  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6272-4640","authenticated-orcid":false,"given":"Zi Qin","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Colon &amp; Rectal Surgery Liverpool Hospital  Sydney New South Wales Australia"},{"name":"Department of General Surgery Royal Perth Hospital  Perth Western Australia Australia"},{"name":"School of Medicine University of New South Wales  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,3]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Colorectal cancer statistics2022[cited 15 Oct. 2023.] Available from URL: https:\/\/www.wcrf.org\/cancer\u2010trends\/colorectal\u2010cancer\u2010statistics\/#:~:text=Colorectal%20(also%20known%20as%20bowel of%20colorectal%20cancer%20in%202020."},{"key":"e_1_2_9_3_1","unstructured":"Bowel cancer (Colorectal cancer) in Australia statistics2019[cited 15 Oct. 2023.] Available from URL:https:\/\/www.canceraustralia.gov.au\/cancer-types\/bowel-cancer\/statistics."},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.21037\/jgo.2019.08.06"},{"key":"e_1_2_9_5_1","first-page":"361","article-title":"Colon cancer adrenal metastasis: case report and review of the literature","volume":"32","author":"Capaldi M","year":"2011","journal-title":"G. Chir."},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s005950300028"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6646"},{"key":"e_1_2_9_8_1","first-page":"216","article-title":"A case of long\u2010term survival after curative resection for synchronous solitary adrenal metastasis from rectal cancer","volume":"30","author":"Chen L","year":"2014","journal-title":"Pak. J. Med. Sci."},{"key":"e_1_2_9_9_1","first-page":"1395","article-title":"Bilateral adrenalectomy in the context of primary adrenal insufficiency due to colorectal cancer metastasis","volume":"16","author":"Alberti JF","year":"2022","journal-title":"Ecancermedicalscience"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3393\/ac.2016.32.2.79"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2021.105759"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/030089161109700526"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.4103\/0377-4929.130932"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12094-009-0350-x"},{"key":"e_1_2_9_15_1","first-page":"337","article-title":"Surgical treatment of isolated lung and adrenal metastasis from colorectal cancer","volume":"83","author":"Cantarini R","year":"2012","journal-title":"Case Rep. Ann. Ital Chir."},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000322508"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.3862\/jcoloproctology.47.582"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02562648"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2020.09.094"},{"key":"e_1_2_9_20_1","first-page":"185","article-title":"A case of solitary arenal tumor metastasized from rectal cancer","volume":"106","author":"Ikeda T","year":"2015","journal-title":"Nihon Hinyokika Gakkai Zasshi."},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/516403"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.49.227"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1015-9584(09)60105-6"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyd104"},{"key":"e_1_2_9_25_1","first-page":"1699","article-title":"A case of rectal cancer with solitary adrenal metastasis","volume":"31","author":"Kato T","year":"2004","journal-title":"Gan To Kagaku Ryoho"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/1757-1626-1-49"},{"key":"e_1_2_9_27_1","first-page":"2116","article-title":"A case of solitary right adrenal metastasis from rectal cancer","volume":"46","author":"Koyama M","year":"2019","journal-title":"Gan To Kagaku Ryoho"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v22.i14.3879"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40792-020-00913-x"},{"key":"e_1_2_9_30_1","first-page":"2536","article-title":"Adrenalectomy for solitary adrenal metastasis from colorectal cancer","volume":"37","author":"Mikayama Y","year":"2010","journal-title":"Gan To Kagaku Ryoho"},{"key":"e_1_2_9_31_1","first-page":"103","article-title":"Exceptional bilateral adrenalectomy after secondaries from colorectal cancer","volume":"51","author":"Moreno\u2010Elola A","year":"2004","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-7258-x"},{"key":"e_1_2_9_33_1","first-page":"2036","article-title":"A case of cecum cancer with synchronous adrenal solitary metastasis","volume":"45","author":"Nakasone Y","year":"2018","journal-title":"Gan To Kagaku Ryoho"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2011.06674.x"},{"key":"e_1_2_9_35_1","first-page":"355","article-title":"A case of brain, lung, and adrenal metastasis from colorectal cancer controlled by loco\u2010regional surgery","volume":"47","author":"Ohta K","year":"2020","journal-title":"Gan To Kagaku Ryoho"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.5833\/jjgs.35.1703"},{"key":"e_1_2_9_37_1","first-page":"2340","article-title":"A case of long\u2010term survival after resection of liver and adrenal metastases from rectal cancer","volume":"42","author":"Okajima C","year":"2015","journal-title":"Gan To Kagaku Ryoho"},{"key":"e_1_2_9_38_1","first-page":"(ePub)","article-title":"Metachronous solitary left adrenal gland metastasis of right colon cancer treated with laparoscopic approach","volume":"85","author":"Oldani A","year":"2014","journal-title":"Ann. Ital. Chir."},{"key":"e_1_2_9_39_1","first-page":"26","article-title":"Multiorgan resection in T4 colonic adenocarcinoma: report of a case","volume":"65","author":"O\u00f1ate\u2010Oca\u00f1a LF","year":"2000","journal-title":"Rev. Gastroenterol. Mex."},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/rjv053"},{"key":"e_1_2_9_41_1","first-page":"362","article-title":"Robotic adrenalectomy for sigmoid colon cancer oligometastasis","volume":"3","author":"Pai VD","year":"2015","journal-title":"Ann. Transl. Med."},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/rjx098"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1177\/030089160709300119"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.5833\/jjgs.34.1670"},{"key":"e_1_2_9_45_1","first-page":"120","article-title":"Solitary adrenal metastasis in a patient with sigmoid colon cancer; report of a case","volume":"37","author":"Shoji Y","year":"2006","journal-title":"Int. J. Gastrointest. Cancer"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.5833\/jjgs.44.1319"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1308\/147870811X591134"},{"key":"e_1_2_9_48_1","first-page":"1751","article-title":"A case of solitary adrenal metastasis from rectal cancer treated by adrenalectomy after preoperative chemotherapy","volume":"43","author":"Tsuchida K","year":"2016","journal-title":"Gan To Kagaku Ryoho"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40792-019-0611-z"},{"key":"e_1_2_9_50_1","first-page":"1370","article-title":"A case of recurrent rectal cancer with adrenal and lung metastasis with more than ten\u2010year survival after surgery","volume":"44","author":"Uchiyama K","year":"2017","journal-title":"Gan To Kagaku Ryoho"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2016.4897"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00309504"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000015244"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(97)00281-X"},{"key":"e_1_2_9_55_1","first-page":"29","article-title":"Adrenal metastases\u2013long\u2010term results of surgical treatment, single\u2010centre experience","volume":"24","author":"Samsel R","year":"2020","journal-title":"Contemp. Oncol."},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2003.08.005"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-008-9235-2"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjsopen\/zrac047"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6603033"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2007.02.093"},{"key":"e_1_2_9_61_1","first-page":"389","article-title":"The role of surgery in the treatment of clinically isolated adrenal metastasis","volume":"82","author":"Kim SH","year":"1998","journal-title":"CA Cancer J."}],"container-title":["ANZ Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.18923","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T13:14:03Z","timestamp":1743858843000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ans.18923"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":60,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1111\/ans.18923"],"URL":"https:\/\/doi.org\/10.1111\/ans.18923","archive":["Portico"],"relation":{},"ISSN":["1445-1433","1445-2197"],"issn-type":[{"value":"1445-1433","type":"print"},{"value":"1445-2197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"2024-02-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}