{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:03:05Z","timestamp":1787504585427,"version":"build-2736575974"},"reference-count":52,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T00:00:00Z","timestamp":1717545600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Clinically relevant postoperative pancreatic fistula (CR\u2010POPF) is a significant complication after pancreaticoduodenectomy. CR\u2010POPF is associated with various adverse outcomes, including high mortality rates. Identifying complication predictors for CR\u2010POPF, such as preoperative CT scan features, including pancreatic attenuation index (PAI) and pancreatic duct diameter (PDD), is critical. This systematic review and meta\u2010analysis consolidate existing literature to assess the impact of these variables on CR\u2010POPF risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Our comprehensive search, conducted in May 2023, covered PubMed, Scopus, Embase, and Web of Science databases. Inclusion criteria encompassed peer\u2010reviewed cohort studies on pancreaticoduodenectomy, focusing on preoperative CT scan data. Case reports, case series, and studies reporting distal pancreatectomy were excluded. The quality assessment of included articles was done using New\u2010Castle Ottawa Scale for cohort studies. Statistical analysis was carried out using Review Manager 5. This study was registered at the International Prospective Register of Systematic Reviews database (PROSPERO) on 12 May 2023 (registration number: CRD42023414139).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We conducted a detailed analysis of 38 studies with 7393 participants. The overall incidence of CR\u2010POPF was 24%. Multiple linear regression analyses revealed that PDD and pancreatic parenchymal thickness were significantly associated with CR\u2010POPF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our systematic review and meta\u2010analysis shed light on CT scan findings for predicting CR\u2010POPF after Whipple surgery. Age, PDD, and pancreatic parenchymal thickness significantly correlate with CR\u2010POPF.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ans.19033","type":"journal-article","created":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T07:33:40Z","timestamp":1717572820000},"page":"1030-1038","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Association of preoperative\n                    <scp>CT\u2010scan<\/scp>\n                    features and clinically relevant postoperative pancreatic fistula after pancreaticoduodenectomy: a\n                    <scp>meta\u2010analysis<\/scp>"],"prefix":"10.1111","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4878-4276","authenticated-orcid":false,"given":"Ahmad","family":"Madankan","sequence":"first","affiliation":[{"name":"Department of Surgery Surgery Research Center, School of Medicine, Rasool\u2010E Akram Hospital, Iran University of Medical 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