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This study aimed to examine the rate and predictors of opioid dispensing and high opioid exposure after hospital discharge from surgery in New Zealand (NZ) between January 2007 to December 2019.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a retrospective population\u2010based cohort study inclusive of all ages and surgical specialties. Data were obtained from the NZ Ministry of Health's national health databases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>1\u2009781\u2009059 patients were included in the study and 20.9% (<jats:italic>n<\/jats:italic>\u2009=\u2009371\u2009882) of surgical patients received opioids within 7\u2009days after hospital discharge. From those who were dispensed with opioids after hospital discharge, 36.6% (<jats:italic>n<\/jats:italic>\u2009=\u2009134\u2009646) had high opioid exposure. Orthopaedic surgery (AOR 6.97; 95% CI 6.82\u20137.13) and history of opioid use (AOR 3.18; 95% CI 2.86\u20133.53) increased the odds of postoperative opioid dispensing and high opioid exposure respectively. Severe multi\u2010morbidity burden (AOR 0.76; 95% CI 0.73\u20130.78) and alcohol misuse (AOR 0.84; 95% CI 0.77\u20130.93) lowered the odds of postoperative opioid dispensing and high opioid exposure respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our findings suggest a concerning rate of high opioid exposure among surgical patients after discharge. The predictors for postoperative opioid dispensing and high opioid exposure identified in our study provide insight into opioid prescribing patterns in NZ and inform future postoperative pain management.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.19115","type":"journal-article","created":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T10:36:03Z","timestamp":1718361363000},"page":"1846-1852","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Rate and predictors of postoperative opioid use and high opioid exposure after surgery in New Zealand: a retrospective study"],"prefix":"10.1111","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-8400-3635","authenticated-orcid":false,"given":"Jessica Xiao Yue","family":"Gao","sequence":"first","affiliation":[{"name":"School of Medicine, Faculty of Medical and Health Sciences University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1291-3902","authenticated-orcid":false,"given":"Amy Hai Yan","family":"Chan","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Faculty of Medical and Health Sciences University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6356-256X","authenticated-orcid":false,"given":"Jiayi","family":"Gong","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Faculty of Medical and Health Sciences University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,14]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2019.10734"},{"key":"e_1_2_10_3_1","first-page":"33","article-title":"Long\u2010term opioid medication use before and after joint replacement surgery in New Zealand","volume":"132","author":"Wilson R","year":"2019","journal-title":"NZ Med. 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