{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T22:20:04Z","timestamp":1780352404561,"version":"3.54.1"},"reference-count":34,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T00:00:00Z","timestamp":1726099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Sarcopenia has a detrimental impact on patient outcomes following colorectal surgery, increasing financial strain on the healthcare system. Given the absence of specific Australian data, this study aimed to measure the cost of sarcopenia in the context of colorectal surgery in an Australian public hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cost analysis, following CHEERS guidelines, was conducted on major elective colorectal cancer surgical cases at the Royal Adelaide Hospital between 2018 and 2022. The cross\u2010sectional psoas area was measured through computed tomography (CT) imaging at the level of the third lumbar vertebrae, and sarcopenia was determined using gender\u2010specific thresholds. Hospital billing data was used to gather costings (AU$).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Out of 271 patients, 57 (21.0%) comprised the sarcopenic group (SG). SG patients were older (74 vs. 69\u2009years, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), had a higher American Society of Anaesthesiologists (&gt;II, 71.9% vs. 53.7%, <jats:italic>P<\/jats:italic>\u2009=\u20090.014) and a lower median body mass index (24.8 vs. 28.7\u2009kg\/m<jats:sup>2<\/jats:sup>, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). The SG exhibited a greater likelihood of complications (84.2 vs. 68.7%, <jats:italic>P<\/jats:italic>\u2009=\u20090.020) and prolonged hospital stay by 1\u2009day (median 7 vs. 6\u2009days, <jats:italic>P<\/jats:italic>\u2009=\u20090.027). Despite an increased mean total cost of hospital admission, no statistically significant difference was found (AU$37 712 vs. $34\u2009845, <jats:italic>P<\/jats:italic>\u2009=\u20090.296). Multivariate analysis revealed hypoalbuminemia, prolonged operative time, postoperative ileus, return to theatre, Clavien\u2010Dindo grade\u2009\u22653 complications, and prolonged stay increased overall cost (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Sarcopenia was not associated with a significantly increased cost of colorectal surgery in our institution. Future studies examining the cost\u2010effectiveness of prehabilitation programmes targeting sarcopenia should be considered.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.19230","type":"journal-article","created":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T14:36:35Z","timestamp":1726151795000},"page":"2038-2046","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Financial implications of sarcopenia in colorectal cancer surgery: a cost analysis in an Australian public hospital"],"prefix":"10.1111","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0327-7334","authenticated-orcid":false,"given":"Luke","family":"Traeger","sequence":"first","affiliation":[{"name":"Colorectal Unit, Department of Surgery Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Adelaide Medical School, Faculty of Health and Medical Sciences University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9330-625X","authenticated-orcid":false,"given":"Sergei","family":"Bedrikovetski","sequence":"additional","affiliation":[{"name":"Colorectal Unit, Department of Surgery Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Adelaide Medical School, Faculty of Health and Medical Sciences University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4483-1204","authenticated-orcid":false,"given":"Rowan V.","family":"David","sequence":"additional","affiliation":[{"name":"College of Medicine and Public Health Flinders University  Bedford Park South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice A.","family":"Jay","sequence":"additional","affiliation":[{"name":"Colorectal Unit, Department of Surgery Royal Adelaide Hospital  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James W.","family":"Moore","sequence":"additional","affiliation":[{"name":"Colorectal Unit, Department of Surgery Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Adelaide Medical School, Faculty of Health and Medical Sciences University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4918-8871","authenticated-orcid":false,"given":"Tarik","family":"Sammour","sequence":"additional","affiliation":[{"name":"Colorectal Unit, Department of Surgery Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Adelaide Medical School, Faculty of Health and Medical Sciences University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,12]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000001633"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-018-3128-1"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-021-03839-4"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.14725"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v8.i7.1188"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/SPC.0000000000000382"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2016.03.003"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000628"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-019-01893-8"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2018.11.003"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2018.09.026"},{"key":"e_1_2_12_13_1","first-page":"93","article-title":"Economic impact of hospitalizations in US adults with sarcopenia","volume":"8","author":"Goates S","year":"2019","journal-title":"J. Frailty Aging"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2016.05.002"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/1747-0080.12287"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2012.350"},{"key":"e_1_2_12_17_1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0186547","article-title":"Low skeletal muscle mass is associated with increased hospital expenditure in patients undergoing cancer surgery of the alimentary tract","volume":"12","author":"Vugt JLA","year":"2017","journal-title":"PLoS One"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f1049"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12805"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(10)70218-7"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181b13ca2"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e318296c732"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e318293ee55"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-013-2148-y"},{"key":"e_1_2_12_25_1","volume-title":"Inflation Calculator","author":"Reserve Bank of Australia","year":"2022"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181cbcc9a"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2006.tb00378.x"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejcn.2016.73"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2013.04.042"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.958261"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-019-1928-0"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-018-3954-z"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000973"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-023-02812-3"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjsopen\/zrad054"}],"container-title":["ANZ Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.19230","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T13:21:40Z","timestamp":1732022500000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ans.19230"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,12]]},"references-count":34,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1111\/ans.19230"],"URL":"https:\/\/doi.org\/10.1111\/ans.19230","archive":["Portico"],"relation":{},"ISSN":["1445-1433","1445-2197"],"issn-type":[{"value":"1445-1433","type":"print"},{"value":"1445-2197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,12]]},"assertion":[{"value":"2024-05-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}