{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:23:39Z","timestamp":1790774619493,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,10,20]],"date-time":"2024-10-20T00:00:00Z","timestamp":1729382400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Non\u2010tuberculous mycobacteria (NTM) are rare causes of bone and joint infection (BJI) and there is limited evidence on which to base management decisions. This study describes 1 year of experience from a multi\u2010disciplinary BJI team which collects data on all cases reviewed at a tertiary referral centre in Queensland, Australia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The database was interrogated for all cases in which NTM were recovered from operative samples. Individual chart review was performed to collect the details of each case.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of seven cases were managed between 1st February 2021 and 28th February 2022, comprising one patient with chronic osteomyelitis, three with fracture\u2010related infections, two with prosthetic joint infections, and one with infection of a synthetic ligament graft. In contrast to pulmonary NTM infections, most patients were clinically well and immunocompetent, and most infections were propagated by direct inoculation. Time to diagnosis was unknown in three patients, with 1, 2, 2, and 5\u2009months for the remaining four. Rapid growing NTM were diagnosed on routine cultures and specific mycobacterial cultures were confirmatory. Management was characterized by multiple stage surgical procedures and prolonged antimicrobial regimens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Antimicrobial complications were common; however, all patients were infection free at their latest follow up. Despite the inherent limitations, these results suggest that routinely ordering mycobacterial culture is of low yield. There is potential for shorter\u2010term oral antimicrobial treatments. Prospective research is required to optimize treatment regimens and durations.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.19268","type":"journal-article","created":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T06:05:27Z","timestamp":1729490727000},"page":"1942-1948","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Non\u2010tuberculous mycobacterial bone and joint infections \u2013 a case series from a tertiary referral centre in Australia"],"prefix":"10.1111","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1574-5892","authenticated-orcid":false,"given":"Cameron","family":"Holscher","sequence":"first","affiliation":[{"name":"Infectious Diseases Unit Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Manzanero","sequence":"additional","affiliation":[{"name":"Jamieson Trauma Institute Metro North Health  Brisbane Queensland Australia"},{"name":"School of Clinical Sciences Queensland University of Technology  Brisbane Queensland Australia"},{"name":"Australian Institute of Bioengineering and Nanotechnology The University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Hume","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"},{"name":"Herston Infectious Diseases Institute Metro North Health  Brisbane Queensland Australia"},{"name":"Microbiology Department, Central Laboratory Pathology Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew L.","family":"Foster","sequence":"additional","affiliation":[{"name":"Jamieson Trauma Institute Metro North Health  Brisbane Queensland Australia"},{"name":"School of Clinical Sciences Queensland University of Technology  Brisbane Queensland Australia"},{"name":"Department of Orthopaedic Surgery Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Tetsworth","sequence":"additional","affiliation":[{"name":"Jamieson Trauma Institute Metro North Health  Brisbane Queensland Australia"},{"name":"Department of Orthopaedic Surgery Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul R.","family":"Chapman","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"},{"name":"Jamieson Trauma Institute Metro North Health  Brisbane Queensland Australia"},{"name":"Herston Infectious Diseases Institute Metro North Health  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa241"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/microbiolspec.TNMI7-0024-2016"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200604-571ST"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.106B1.BJJ-2023-0279.R2"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pulmoe.2017.12.005"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/23744235.2015.1040445"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.96B11.33427"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2506.181041"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2019.07.006"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.104B1.BJJ-2021-0876.R1"},{"key":"e_1_2_7_12_1","unstructured":"FosterAL ChapmanPR HumeA et al.Establishing mDRIFT \u2013 a multidisciplinary device related infection team. 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