{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T10:33:38Z","timestamp":1785666818855,"version":"3.56.0"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T00:00:00Z","timestamp":1736380800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100015539","name":"Australian Government","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015539","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004331","name":"Johnson and Johnson","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004331","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020021","name":"Avant Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020021","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100028184","name":"Apollo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100028184","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016303","name":"Medtronic Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016303","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020453","name":"W. L. Gore and Associates","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020453","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To determine if the positive outcomes from clinical trials regarding the safety and efficacy of metabolic bariatric surgery are reproducible at a national level.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A longitudinal registry\u2010based observation study with data collected from all persons undergoing metabolic bariatric surgery in Australia from 28 February 2012\u201331 December 2021 including data from 122,567 index patients who underwent 134,625 completed bariatric procedures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcomes and Measures<\/jats:title><jats:p>Defined adverse outcomes at 90\u2010days (unplanned readmission, intensive care admission and re\u2010operation; death), annual change in weight (percent total body weight loss (TBWL)), diabetes treatment and need for re\u2010operation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>79.0% of participants were female. Mean age on the day of surgery was 44.0\u2009years (SD 11.8; range 12.9\u201087.9\u2009years) and mean BMI 41.7 kg\/m2 (SD 7.6). At 5\u2010years participants who underwent one anastomosis gastric bypass had TBWL 34.88% (SD 8.67%), roux\u2010en\u2010Y gastric bypass 30.73 % (SD 9.47%); sleeve gastrectomy 26.5% (SD 10.5%) and adjustable gastric bands 17.6% (SD 12.1%). At 90\u2010days 3.6% of procedures recorded a defined adverse event. 13,904 (13.6%) primary participants reported being treated for diabetes at baseline. No medication for diabetes was required by 71.6% (follow\u2010up 58%) at 1\u2010year and 61% (follow\u2010up 22%) at 5\u2010years.<\/jats:p><jats:p>13\u2009904 (13.6%) primary participants reported being treated for diabetes at baseline. No medication for diabetes was required by 71.6% (follow\u2010up 58%) at 1\u2010year and 61% (follow\u2010up 22%) at 5\u2010years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Metabolic bariatric surgery is safe and induces substantial weight loss with reduced need for diabetes medications in the real\u2010world.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">ClinicalTrials.gov<\/jats:ext-link> ID<\/jats:title><jats:p>NCT03441451.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.19378","type":"journal-article","created":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T12:19:23Z","timestamp":1736425163000},"page":"895-903","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Metabolic bariatric surgery generates substantial, sustained weight loss and health improvement in a real\u2010world setting"],"prefix":"10.1111","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0137-2688","authenticated-orcid":false,"given":"Wendy A.","family":"Brown","sequence":"first","affiliation":[{"name":"Bariatric Surgery Registry, Central Clinical School Monash University  Melbourne Victoria Australia"},{"name":"Monash University Department of Surgery Central Clinical School, Alfred Health  Melbourne Victoria Australia"},{"name":"Oesophago\u2010Gastric and Bariatric Unit Alfred Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dianne L.","family":"Brown","sequence":"additional","affiliation":[{"name":"Bariatric Surgery Registry, Central Clinical School Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer F.","family":"Holland","sequence":"additional","affiliation":[{"name":"Bariatric Surgery Registry, Central Clinical School Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angus","family":"Campbell","sequence":"additional","affiliation":[{"name":"Bariatric Surgery Registry, Central Clinical School Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenifer","family":"Cottrell","sequence":"additional","affiliation":[{"name":"Bariatric Surgery Registry, Central Clinical School Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9413-6897","authenticated-orcid":false,"given":"Susannah","family":"Ahern","sequence":"additional","affiliation":[{"name":"Bariatric Surgery Registry, Central Clinical School Monash University  Melbourne Victoria Australia"},{"name":"School of Public Health Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7109-8493","authenticated-orcid":false,"given":"Jennifer","family":"Reilly","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Perioperative Medicine Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Garduce","sequence":"additional","affiliation":[{"name":"Bariatric Surgery Registry, Central Clinical School Monash University  Melbourne Victoria Australia"},{"name":"School of Public Health Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Wetter","sequence":"additional","affiliation":[{"name":"Bariatric Surgery Registry, Central Clinical School Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey M.","family":"Hamdorf","sequence":"additional","affiliation":[{"name":"Bariatric Surgery Registry, Central Clinical School Monash University  Melbourne Victoria Australia"},{"name":"Discipline of Surgery, Medical School The University of Western Australia  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Talbot","sequence":"additional","affiliation":[{"name":"Bariatric Surgery Registry, Central Clinical School Monash University  Melbourne Victoria Australia"},{"name":"Department of Surgery University of New South Wales St George and Sutherland Clinical School  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Baker","sequence":"additional","affiliation":[{"name":"Bariatric Surgery Registry, Central Clinical School Monash University  Melbourne Victoria Australia"},{"name":"Department of Surgery Mater Private Hospital  Townsville Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew D.","family":"MacCormick","sequence":"additional","affiliation":[{"name":"Bariatric Surgery Registry, Central Clinical School Monash University  Melbourne Victoria Australia"},{"name":"Department of Surgery University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian D.","family":"Caterson","sequence":"additional","affiliation":[{"name":"Bariatric Surgery Registry, Central Clinical School Monash University  Melbourne Victoria Australia"},{"name":"Boden Initiative, Charles Perkins Centre University of Sydney  New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,9]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.12567"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2002449"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-020-05207-7"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.11459"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.11525"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61116-8"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000002794"},{"key":"e_1_2_11_9_1","volume-title":"Registries for evaluating patient outcomes: a user's guide","author":"Gliklich RE","year":"2014"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/ans.17438"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13679-017-0286-3"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000003512"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-024-07196-3"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000003279"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2017.59"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)33102-1"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc18-S007"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.4239\/wjd.v14.i4.396"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002985"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2589-7500(23)00135-8"},{"key":"e_1_2_11_21_1","first-page":"1489","article-title":"Patient and healthcare practitioner evaluation of patient\u2010reported outcomes in bariatric surgery: a modified Delphi study","volume":"48","author":"Budin AJ","year":"2024","journal-title":"Int. J. Obes. (Lond)"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-024-07381-4"}],"container-title":["ANZ Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.19378","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T12:13:48Z","timestamp":1748261628000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ans.19378"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,9]]},"references-count":21,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1111\/ans.19378"],"URL":"https:\/\/doi.org\/10.1111\/ans.19378","archive":["Portico"],"relation":{},"ISSN":["1445-1433","1445-2197"],"issn-type":[{"value":"1445-1433","type":"print"},{"value":"1445-2197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,9]]},"assertion":[{"value":"2024-11-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}