{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T04:00:16Z","timestamp":1761796816350,"version":"build-2065373602"},"reference-count":18,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T00:00:00Z","timestamp":1747699200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001529","name":"Waikato Medical Research Foundation","doi-asserted-by":"publisher","award":["343"],"award-info":[{"award-number":["343"]}],"id":[{"id":"10.13039\/501100001529","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Backgrounds<\/jats:title>\n                    <jats:p>We aimed to assess the pattern, management, and outcomes of recurrent pseudomyxoma peritonei (PMP) following cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) and compare repeat and index CRS\/HIPEC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective review was performed of patients undergoing CRS\/HIPEC for PMP between 01\/01\/2008 and 30\/06\/2022 at a tertiary referral center in New Zealand. Multivariate logistic regression was used to identify independent predictors of repeat CRS\/HIPEC. Overall survival (OS) of PMP recurrence was stratified according to management strategy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 183 primary CRS\/HIPEC for appendiceal PMP, 154 (84.2%) achieved complete cytoreduction. Median follow\u2010up duration was 72.1\u2009months. Forty\u2010nine recurred (31.8%). 40 (81.6%) cases of recurrence were isolated to the peritoneal cavity, and 47 (95.9%) occurred within 5\u2009years. 27 (55.1%) underwent repeat curative\u2010intent surgery. 22 (44.9%) were managed with palliative intent. Age &gt;\u200965 and high\u2010grade carcinoma peritonei (HG) were independent negative predictors of repeat curative\u2010intent surgery. Five\u2010year overall survival was significantly higher in patients undergoing repeat curative\u2010intent surgery (80.3%) compared to those managed with palliative intent (44.8%) (HR\u2009=\u20090.23,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Curative\u2010intent repeat surgery was an independent predictor of overall survival in PMP recurrences. Compared to primary CRS\/HIPEC, repeat CRS\/HIPEC were less extensive procedures conducted in cases with a lower peritoneal cancer index. Repeat CRS\/HIPEC had similar peri\u2010operative morbidity and long\u2010term survival to primary procedures.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Repeat CRS\/HIPEC for recurrent PMP is feasible and has similar safety and efficacy to index operations. Favorable long\u2010term outcomes are achievable in well\u2010selected patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ans.70179","type":"journal-article","created":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T07:50:19Z","timestamp":1747727419000},"page":"2104-2111","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Pattern, Management, and Outcomes of Recurrence Following Cytoreductive Surgery for Pseudomyxoma Peritonei"],"prefix":"10.1111","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2167-1500","authenticated-orcid":false,"given":"Rennie Xinrui","family":"Qin","sequence":"first","affiliation":[{"name":"Department of General Surgery Te Whatu Ora Waikato  Hamilton New Zealand"},{"name":"School of Population Health, Faculty of Medical and Health Sciences University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tilisi","family":"Puloka","sequence":"additional","affiliation":[{"name":"Department of General Surgery Te Whatu Ora Waikato  Hamilton New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia Hui","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of General Surgery Te Whatu Ora Waikato  Hamilton New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caro","family":"Staheli","sequence":"additional","affiliation":[{"name":"Department of General Surgery Te Whatu Ora Waikato  Hamilton New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simione","family":"Lolohea","sequence":"additional","affiliation":[{"name":"Department of General Surgery Te Whatu Ora Waikato  Hamilton New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasen","family":"Ly","sequence":"additional","affiliation":[{"name":"Department of General Surgery Te Whatu Ora Waikato  Hamilton New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3366-5629","authenticated-orcid":false,"given":"Jesse","family":"Fischer","sequence":"additional","affiliation":[{"name":"Department of General Surgery Te Whatu Ora Waikato  Hamilton New Zealand"},{"name":"Waikato Clinical Campus, Faculty of Medical and Health Sciences University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,20]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2007.04.002"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.39.7166"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199501000-00004"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10147-017-1217-8"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-022-12367-6"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-019-08141-w"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ans.18777"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4613-1247-5_23"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000535"},{"issue":"5","key":"e_1_2_13_11_1","first-page":"518","article-title":"Proposed Classification of Complications of Surgery With Examples of Utility in Cholecystectomy","volume":"111","author":"Clavien P. 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