{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T01:46:53Z","timestamp":1792460813886,"version":"4.5.0"},"reference-count":20,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T00:00:00Z","timestamp":1752192000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006606","name":"Natural Science Foundation of Tianjin Municipality","doi-asserted-by":"publisher","award":["12JCYBJC32700"],"award-info":[{"award-number":["12JCYBJC32700"]}],"id":[{"id":"10.13039\/501100006606","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2025,12]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n Emergency abdominal surgery involves complex, diverse conditions with high patient variability, posing recovery challenges. While Enhanced Recovery After Surgery (ERAS) programs benefit elective surgery and show promise in emergencies, current research is disease\u2010specific, limiting broad assessment. This study evaluates ERAS safety\/effectiveness across multiple emergency abdominal conditions and identifies recovery risk factors.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n This single\u2010blind trial randomized 305 emergency abdominal surgery patients to ERAS (\n n<\/jats:italic>\n \u2009=\u2009151) or conventional care (\n n<\/jats:italic>\n \u2009=\u2009154). ERAS patients underwent perioperative enhanced recovery programs, while controls received conventional management. The primary outcome was time to postoperative recovery criteria. Secondary outcomes included first postoperative flatus\/semi\u2010liquid diet tolerance time, complication rates, maximum pain scores (days 1\u20135), 30\u2010day readmissions, and satisfaction. Data were analyzed via\n t<\/jats:italic>\n \u2010tests, Mann\u2013Whitney U, Fisher's exact tests, and multivariate regression (\n p<\/jats:italic>\n \u2009<\u20090.05 significance).\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n ERAS reduced median recovery time (141\u2009h [IQR: 114\u2013179] vs. 163\u2009h [IQR: 131\u2013204],\n p\u2009<<\/jats:italic>\n \u20090.001), accelerated gastrointestinal recovery (first flatus: 1.10 vs. 1.30\u2009days; semi\u2010liquid tolerance: 3.60 vs. 4.10\u2009days, both\n p\u2009<<\/jats:italic>\n \u20090.05), and improved satisfaction (95 vs. 91,\n p\u2009<<\/jats:italic>\n \u20090.001). No differences in complications (11.9% vs. 15.6%,\n p\u2009=<\/jats:italic>\n \u20090.353) or 30\u2010day readmissions (2.0% vs. 2.6%,\n p<\/jats:italic>\n \u2009>\u20090.999). Shock index and APACHE II were common risk factors; ERAS\u2010specific risks included SOFA (OR\u2009=\u20091.31, 1.03\u20131.71,\n p\u2009=<\/jats:italic>\n \u20090.034), preoperative hemoglobin (OR\u2009=\u20090.95, 0.89\u20131.00,\n p\u2009=<\/jats:italic>\n \u20090.046), preparation time (OR\u2009=\u20090.33, 0.14\u20130.68,\n p\u2009=<\/jats:italic>\n \u20090.005), and blood transfusion (OR\u2009=\u20090.01, 0.00\u20130.23,\n p\u2009=<\/jats:italic>\n \u20090.003).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n ERAS enhances postoperative recovery and satisfaction in emergency abdominal surgery without increasing complications\/readmissions. Identified risk factors support personalized protocols, advancing ERAS implementation.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ans.70251","type":"journal-article","created":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T12:29:16Z","timestamp":1752236956000},"page":"2579-2591","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Enhanced Recovery After Surgery Programs Safely Accelerate Recovery in Emergency Abdominal Surgery: A Randomized Controlled Trial With Multivariable Risk Profiling"],"prefix":"10.1111","volume":"95","author":[{"given":"Jianing","family":"Lu","sequence":"first","affiliation":[{"name":"Department of Anorectal Surgery Wuxi Huishan District People's Hospital Wuxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhuang","sequence":"additional","affiliation":[{"name":"Department of Health Service, Military Health Education Section Logistics College of People's Armed Police Force Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenglu","family":"Wang","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory for Organ Transplantation, Tianjin First Central Hospital Tianjin Medical University Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7386-7084","authenticated-orcid":false,"given":"Hong","family":"Zheng","sequence":"additional","affiliation":[{"name":"Organ Transplant Department, Tianjin First Central Hospital Tianjin Medical University Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Anus and Intestine Surgery Tianjin Hospital Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6878-9293","authenticated-orcid":false,"given":"Dejun","family":"Kong","sequence":"additional","affiliation":[{"name":"School of Medicine Nankai University Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinliang","family":"Duan","sequence":"additional","affiliation":[{"name":"School of Medicine Nankai University Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaofeng","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Medicine Nankai University Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Medicine Nankai University Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,11]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13017-023-00520-9"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.11392"},{"issue":"12","key":"e_1_2_11_4_1","article-title":"Enhanced Recovery After Surgery (ERAS) Approach: A Medical Complex Experience","volume":"15","author":"Elsenosy A. 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A Cohort Study of 468 Nonmetastatic Colorectal Cancer Patients","volume":"135","author":"Pisarska\u2010Adamczyk M.","year":"2025","journal-title":"Polskie Archiwum Medycyny Wewn\u0119trznej"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.59249\/JOAP6662"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.23736\/S0375-9393.23.17389-5"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.4103\/aer.AER_190_17"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/aas.13476"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.21614\/chirurgia.116.6.737"}],"container-title":["ANZ Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.70251","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T07:53:31Z","timestamp":1766217211000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ans.70251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,11]]},"references-count":20,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1111\/ans.70251"],"URL":"https:\/\/doi.org\/10.1111\/ans.70251","archive":["Portico"],"relation":{},"ISSN":["1445-1433","1445-2197"],"issn-type":[{"value":"1445-1433","type":"print"},{"value":"1445-2197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,11]]},"assertion":[{"value":"2025-04-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}