{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T12:04:49Z","timestamp":1792843489160,"version":"4.5.0"},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T00:00:00Z","timestamp":1764288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T00:00:00Z","timestamp":1764288000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2026,4]]},"abstract":"ABSTRACT<\/jats:title>\n \n Introduction<\/jats:title>\n \n Melioidosis (organism:\n \n Burkholderia pseudomallei<\/jats:italic>\n <\/jats:styled-content>\n ) is an uncommon but serious cause of mycotic aortic aneurysms in endemic areas of North Queensland and Southeast Asia. This study describes the presentation, management, and outcomes of melioidosis\u2010associated aortic aneurysms at a regional tertiary centre.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A retrospective review of all open and endovascular aortic aneurysm repairs recorded in the Australasian Vascular Audit and in the institutional electronic database between 1 January 2019 and 15 May 2025 was performed. Patient demographics, comorbidities (including ischaemic heart disease, type 2 diabetes, hypertension, end\u2010stage renal failure, and smoking status), aneurysm characteristics (location and maximum diameter), procedural details (repair type, American Society of Anesthesiologists (ASA) score and device selection) and outcomes at 30\u2009days, 90\u2009days and 12\u2009months were collected.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Among 217 AAA repairs (17 open, 200 EVAR), six (2.8%) were mycotic and, of these, five (2.3%) yielded\n \n B. pseudomallei<\/jats:italic>\n <\/jats:styled-content>\n on culture. Four patients presented as emergency ruptures, while one with an ectatic aorta was referred electively by the infectious diseases team. Aneurysm diameters ranged from 30\u2009mm to 60\u2009mm, all involving the infrarenal aorta or aortoiliac segment. Two patients (40%) died\u2014one from gastrointestinal complications within 30\u2009days and another from an unrelated cardiac event at 12\u2009months. The other three recovered without further aneurysm\u2010related issues.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Although rare, melioidosis aortic aneurysms in endemic regions almost invariably present as surgical emergencies and carry a high risk of both early and late mortality. These findings highlight the necessity of prompt imaging, targeted microbiological diagnosis, and rapid initiation of either endovascular or open repair together with appropriate antimicrobial therapy. Multicentre studies are needed to refine long\u2010term management strategies and antibiotic protocols for this life\u2010threatening infection.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ans.70400","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T13:13:42Z","timestamp":1764335622000},"page":"862-866","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Melioidosis Aortic Aneurysms, 2019\u20132025: Incidence, Management and Outcomes From a Regional Tertiary Centre in North Queensland"],"prefix":"10.1111","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1735-7845","authenticated-orcid":false,"given":"Oh Sung","family":"Choy","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery Townsville University Hospital Townsville Queensland Australia"},{"name":"College of Medicine and Dentistry James Cook University Townsville Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery Townsville University Hospital Townsville Queensland Australia"},{"name":"College of Medicine and Dentistry James Cook University Townsville Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vimalin","family":"Vedanayagam","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery Townsville University Hospital Townsville Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramesh","family":"Velu","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery Townsville University Hospital Townsville Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,28]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.024021"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000364"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0012485"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0008525"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2024.107480"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-017-1450-7"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2010.05.090"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2015.12.011"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.114.001513"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-32100-2"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2712.211302"}],"container-title":["ANZ Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.70400","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ans.70400","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.70400","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:39:22Z","timestamp":1777523962000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ans.70400"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,28]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1111\/ans.70400"],"URL":"https:\/\/doi.org\/10.1111\/ans.70400","archive":["Portico"],"relation":{},"ISSN":["1445-1433","1445-2197"],"issn-type":[{"value":"1445-1433","type":"print"},{"value":"1445-2197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,28]]},"assertion":[{"value":"2025-06-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}