{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T17:29:34Z","timestamp":1772990974821,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"1-2","license":[{"start":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2026,1]]},"abstract":"ABSTRACT<\/jats:title>\n \n Backgrounds<\/jats:title>\n Endoscopic retrograde cholangiopancreatography (ERCP) is a diagnostic and therapeutic procedure for biliary and pancreatic diseases. Post\u2010ERCP pancreatitis (PEP) is a common complication. The efficacy of somatostatin and octreotide for PEP prevention is controversial. This study aimed to compare somatostatin and octreotide formulations for PEP prevention.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A retrospective trial analyzed patients undergoing\n ERCP<\/jats:styled-content>\n , stratified by medication type and dosage. The primary outcome was\n PEP<\/jats:styled-content>\n incidence. Secondary outcomes included hyperamylasemia incidence, the duration of hospitalization due to pancreatitis, and postoperative pancreatic function. Post\u2010\n ERCP<\/jats:styled-content>\n complications and adverse events were recorded to evaluate safety.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 191 patients undergoing 202\n ERCP<\/jats:styled-content>\n procedures were analyzed. The overall incidences of\n PEP<\/jats:styled-content>\n and hyperamylasemia were 12.4% and 10.9%, respectively. There was no significant difference in\n PEP<\/jats:styled-content>\n incidence between the somatostatin and octreotide groups (13.1% vs. 9.7%,\n p<\/jats:italic>\n >\u20090.05).\n PEP<\/jats:styled-content>\n incidence was significantly lower in the high\u2010dose somatostatin group compared to the low\u2010dose group (1.8% vs. 20%,\n p<\/jats:italic>\n <\u20090.05), and in the high\u2010dose octreotide group compared to the low\u2010dose group (0.0% vs. 18.8%,\n p<\/jats:italic>\n <\u20090.05). No significant differences in hyperamylasemia rates, post\u2010\n ERCP<\/jats:styled-content>\n amylase and lipase levels, duration of hospitalization due to pancreatitis, complications, and adverse events were observed across groups.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n High\u2010dose somatostatin (at least 6\u2009mg) or octreotide (at least 0.5\u2009mg) within 24\u2009h after\n ERCP<\/jats:styled-content>\n are suggested for preventing\n PEP<\/jats:styled-content>\n in patients at average risk.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ans.70471","type":"journal-article","created":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T12:01:07Z","timestamp":1767787267000},"page":"218-223","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative Effectiveness of Somatostatin and Octreotide for Preventing Pancreatitis After Endoscopic Retrograde Cholangiopancreatography: A Retrospective Study"],"prefix":"10.1111","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7402-430X","authenticated-orcid":false,"given":"Zijun","family":"Fan","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Affiliated Hospital of Jiangnan University Wuxi Jiangsu Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yilin","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Affiliated Hospital of Jiangnan University Wuxi Jiangsu Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingyue","family":"Sheng","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Affiliated Hospital of Jiangnan University Wuxi Jiangsu Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tianhao","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Affiliated Hospital of Jiangnan University Wuxi Jiangsu Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tielong","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Affiliated Hospital of Jiangnan University Wuxi Jiangsu Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenhui","family":"Duan","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Affiliated Hospital of Jiangnan University Wuxi Jiangsu Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuzheng","family":"Xue","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Affiliated Hospital of Jiangnan University Wuxi Jiangsu Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2022.09.011"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-017-1359-5"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(02)70431-8"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2001.01015.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1726-4901(09)70002-4"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1377306"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2006.10.030"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2003.03297.x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2007.04928.x"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2006.00959.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2006.03.934"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200363170-00003"},{"issue":"6","key":"e_1_2_9_14_1","first-page":"466","article-title":"Meta\u2010Analysis: Somatostatin for Prophylaxis Against Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis","volume":"54","author":"Pan S. 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