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This study aimed to identify temporal trends in incidence, survival and pancreatectomy uptake in New South Wales (NSW), in patients aged 50\u2009years and older diagnosed with pancreatic and periampullary cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study linked NSW Hospitalisation, Death, and Cancer Registry data. Analysis included patients aged 50\u2009years and older diagnosed or admitted for pancreatic or periampullary cancer (2009\u20132018). We analysed temporal trends in incidence and age\u2010standardised rates of pancreatic cancer, pancreatectomy rates, and 1\u2010, 3\u2010 and 5\u2010year post\u2010diagnosis survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirteen thousand five hundred and sixty patients were identified, with annual cases increasing from 1148 to 1591. Age\u2010standardised pancreatic cancer rates increased from 50.3\/100\u2009000 to 56.3\/100\u2009000 population, an annual increase from 2009 to 2018 of 1.5% (95% CI 1.0\u20132.0). From 2009 to 2018, one\u2010 (27.7% vs. 39.7%) and three\u2010 (13.8% vs. 20.9%) year survival improved, and an increased proportion of patients underwent resection (14.5% to 21.4%). Five\u2010year survival similarly improved (11.6% vs. 19.0%) between 2009 and 2016. Pancreaticoduodenectomy rates decreased, and non\u2010pancreaticoduodenectomy resection rates increased. An increased proportion of pancreatectomies were conducted in high volume centres (\u2265\u200916 pancreatectomies). Diagnosis in a later year improved survival in both the whole, and the surgical cohorts at all endpoints.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In NSW, rates of pancreatic and periampullary cancer in people aged 50\u2009years and older have risen. Despite remaining a disease of high mortality, survival has improved over a 10\u2010year period, and resection is increasingly utilised.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ans.70559","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T12:33:21Z","timestamp":1772973201000},"page":"912-928","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Temporal Trends in Pancreatic Cancer in New South Wales, Australia: A Longitudinal Population\u2010Based Study of Incidence, Surgery and Survival"],"prefix":"10.1111","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8497-2951","authenticated-orcid":false,"given":"Joshua","family":"Mok","sequence":"first","affiliation":[{"name":"School of Clinical Medicine, UNSW, Prince of Wales Clinical School  Sydney 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